Publication Name	World Journal of Psychiatry
Manuscript ID	108525
Country	United States

Category	Psychiatry
Manuscript Type	Systematic Reviews
Article Title	Diagnostic algorithm for clozapine-induced myocarditis: A systematic review
Manuscript Source	Unsolicited Manuscript
All Author List	Yassir Mahgoub, Rawan Alhau, Yumna Magzoub, Aya Ali, Eptihal Nour, Mustafa E E Saeed, Sameera G M Mohamed, Ahmed O S Hassan and Omaima Ali
Funding Agency and Grant Number
Corresponding Author	Yassir Mahgoub, Associate Professor, MD, Department of Psychiatry and Behavioral Health, Penn State College of Medicine, 500 University Dr, Hershey, PA 17033, United States. ymahgoub@pennstatehealth.psu.edu
Key Words	Clozapine; Myocarditis; Pneumonia; Rechallenge; Protocol; Multidisciplinary management
Core Tip	This systematic review proposes a multidisciplinary diagnostic algorithm for clozapine-induced myocarditis to reduce misdiagnosis with clozapine-induced pneumonia. Integrating chest computed tomography to exclude clozapine-induced pneumonia, cardiac magnetic resonance imaging for clozapine-induced myocarditis confirmation, and echocardiography in resource-limited settings, the protocol emphasizes slower clozapine titration and collaboration with cardiology to enhance diagnostic accuracy and ensure the safe use of clozapine in the treatment of treatment-resistant schizophrenia.
Citation	Mahgoub Y, Alhau R, Magzoub Y, Ali A, Nour E, Saeed MEE, Mohamed SGM, Hassan AOS, Ali O. Diagnostic algorithm for clozapine-induced myocarditis: A systematic review. World J Psychiatry 2025; In press

Received	2025-04-17 11:20
Peer-Review Started	2025-04-18 00:53
To Make the First Decision
Return for Revision	2025-05-13 12:20
Revised	2025-05-14 01:12
Second Decision	2025-07-07 02:45
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-07-15 01:27
Articles in Press	2025-07-15 01:27
Publication Fee Transferred	2025-06-03 03:11
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	2220-3206 (online)
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