Publication Name	World Journal of Hepatology
Manuscript ID	108677
Country	United States

Category	Gastroenterology & Hepatology
Manuscript Type	Case Control Study
Article Title	Patient factors in responders and non-responders treated with steroids for acute alcohol-associated hepatitis
Manuscript Source	Unsolicited Manuscript
All Author List	Kent W Sabatose, Alexandra Baker, Kevin Kugler, Jude Delikat, Bethany Jowers, Ambuj Kumar, Sadaf Aslam, Jacentha Buggs, Christine Machado-Denis, Nyingi Kemmer, Kiran Dhanireddy and Rashid Syed
Funding Agency and Grant Number
Corresponding Author	Rashid Syed, MD, Department of Transplant Hepatology, University of South Florida, Tampa General Medical Group, 409 Bayshore Blvd, Tampa, FL 33606, United States. rashid.syed@gmail.com
Key Words	Acute alcohol-associated hepatitis; Steroids; Transplant; Steroid response; Phosphatidylethanol
Core Tip	Steroid therapy for alcohol-associated hepatitis (AAH) remains the primary therapy despite poor predictability of efficacy. Phosphatidylethanol (PEth) value and other biomarkers were analyzed as predictors of steroid therapy response in the treatment of AAH. PEth value was a poor predictor of steroid therapy response, though pre-steroid biochemical markers of liver response to alcohol consumption significantly correlated with steroid response. Identification of non-responders to steroids can direct these patients to earlier enrollment in liver transplantation and avoid unnecessary medical cost.
Citation	Sabatose KW, Baker A, Kugler K, Delikat J, Jowers B, Kumar A, Aslam S, Buggs J, Machado-Denis C, Kemmer N, Dhanireddy K, Syed R. Patient factors in responders and non-responders treated with steroids for acute alcohol-associated hepatitis. World J Hepatol 2025; In press

Received	2025-04-20 03:53
Peer-Review Started	2025-04-29 09:02
To Make the First Decision
Return for Revision	2025-06-03 02:39
Revised	2025-06-11 23:04
Second Decision	2025-07-15 02:40
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-07-15 07:34
Articles in Press	2025-07-15 07:34
Publication Fee Transferred	2025-06-13 12:09
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1948-5182 (online)
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