Publication Name	World Journal of Hepatology
Manuscript ID	108678
Country	United States

Category	Gastroenterology & Hepatology
Manuscript Type	Minireviews
Article Title	Chronic hepatitis C and the risk for atherosclerotic and cardiomyopathic heart disease
Manuscript Source	Unsolicited Manuscript
All Author List	Ismail Elkhattib, Kareem Wael Raafat, Basant Elsayed and Mohamed Elnaggar
Funding Agency and Grant Number
Corresponding Author	Ismail Elkhattib, MD, Division of Gastroenterology and Hepatology,, University of Nebraska Medical Center, 80 Seymour Street, Omaha, NE 68105, United States. ismailkhattib89@gmail.com
Key Words	Hepatitis C virus; Chronic hepatitis C; Cardiovascular disease; Carotid atherosclerosis; Cardiomyopathy; Immune dysregulation; Myocarditis
Core Tip	Hepatitis C virus (HCV) infection has been shown to contribute to cardiovascular complications, extending beyond its liver-related effects. This review highlights the link between HCV and various examples of these complications, such as atherosclerosis and cardiomyopathy, emphasizing the roles of chronic inflammation, oxidative stress, immune dysregulation, and coagulation imbalance. Understanding these mechanisms may help guide future research and improve cardiovascular risk assessment and management in patients with chronic HCV infection.
Citation	Elkhattib I, Raafat KW, Elsayed B, Elnaggar M. Chronic hepatitis C and the risk for atherosclerotic and cardiomyopathic heart disease. World J Hepatol 2025; In press

Received	2025-04-20 03:54
Peer-Review Started	2025-04-29 09:03
To Make the First Decision
Return for Revision	2025-05-22 11:20
Revised	2025-06-05 04:37
Second Decision	2025-07-09 02:39
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-07-09 08:34
Articles in Press	2025-07-09 08:34
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1948-5182 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
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