Publication Name	World Journal of Gastrointestinal Oncology
Manuscript ID	108747
Country	Türkiye

Category	Surgery
Manuscript Type	Letter to the Editor
Article Title	Innovative insights into gut microbiota modulation in colorectal cancer: From microbial dysbiosis to therapeutic strategies
Manuscript Source	Invited Manuscript
All Author List	Semra Demirli Atici
Funding Agency and Grant Number
Corresponding Author	Semra Demirli Atici, MD, Department of General Surgery, Acibadem Kent Hospital, Ataşehir Mahallesi 8229/1, Sokak, Izmir 35620, Türkiye. smrdemirli@hotmail.com
Key Words	Colorectal cancer; Fecal microbiota transplantation; Gut oncomicrobiome signatures; Gut oncology index; Gut microbiota; Microbiota-informed risk stratification
Core Tip	This article clarifies the complex involvement of the gut microbiota in colorectal cancer (CRC), emphasizing the influence of microbial metabolites, immunological interactions, biofilm formation, and the therapeutic potential of fecal microbiota transplantation. It also presents innovative future directions, including engineered probiotics and microbiota-informed risk stratification models, which may advance precision oncology in CRC care.
Citation	Demirli Atici S. Innovative insights into gut microbiota modulation in colorectal cancer: From microbial dysbiosis to therapeutic strategies. World J Gastrointest Oncol 2025; In press

Received	2025-04-22 05:55
Peer-Review Started	2025-04-22 05:55
To Make the First Decision
Return for Revision	2025-05-09 09:31
Revised	2025-06-02 19:36
Second Decision	2025-06-27 02:37
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-06-27 06:52
Articles in Press	2025-06-27 06:52
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1948-5204 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
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