Publication Name	World Journal of Gastrointestinal Pathophysiology
Manuscript ID	108952
Country	Denmark

Category	Gastroenterology & Hepatology
Manuscript Type	Review
Article Title	Gut-skin axis: Emerging insights for gastroenterologists-a narrative review
Manuscript Source	Invited Manuscript
All Author List	Neeraj Singla, Khayati Singla, Mohamed Attauabi and Dhruv Aggarwal
Funding Agency and Grant Number
Corresponding Author	Mohamed Attauabi, Department of Gastroenterology and Hepatology, Copenhagen University Hospital - Herlev and Gentofte, Borgmester Ib Juuls Vej 1, DK-2730 Herlev, Copenhagen 2730, Hovedstaden, Denmark. mohamed.attauabi.01@regionh.dk
Key Words	Gut-skin axis; Microbiome; Inflammatory bowel disease; Celiac disease; Psoriasis; Dysbiosis; Atopic dermatitis; Probiotics; Faecal microbiota transplant
Core Tip	The gut-skin axis reflects a robust bidirectional connection between the gut and skin, driven by immune and metabolic pathways. Intestinal dysbiosis is a key driver of systemic inflammation, impacting both the gut and skin. Dietary influences, atopy, and microbial modulation play critical roles in this interplay. Skin disorders like atopic dermatitis (AD), hidradenitis suppurativa, psoriasis have association with gastrointestinal (GI) diseases. They might also serve as an early marker of underlying GI pathology. Microbiome-targeted therapies like probiotics and fecal microbiota transplantation offer promising avenues in the management of skin disorders like psoriasis, AD and acne rosacea rooted in gut dysregulation.
Citation	Singla N, Singla K, Attauabi M, Aggarwal D. Gut-skin axis: Emerging insights for gastroenterologists-a narrative review. World J Gastrointest Pathophysiol 2025; In press

Received	2025-04-28 11:05
Peer-Review Started	2025-04-28 11:05
To Make the First Decision
Return for Revision	2025-05-22 17:50
Revised	2025-06-05 15:01
Second Decision	2025-08-25 03:52
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-08-25 12:39
Articles in Press	2025-08-25 12:39
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	2150-5330 (online)
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