Publication Name	World Journal of Clinical Pediatrics
Manuscript ID	109022
Country	India

Category	Infectious Diseases
Manuscript Type	Randomized Controlled Trial
Article Title	Efficacy of prophylactic intermittent zinc supplementation for reducing acute respiratory infections and diarrhoea in infants:a randomized controlled trial
Manuscript Source	Invited Manuscript
All Author List	Chandra Mohan Kumar, Arnab Ghorui and Karuna Hamsay
Funding Agency and Grant Number
Corresponding Author	Arnab Ghorui, Department of Paediatrics, All India Institute of Medical Sciences, Phulwarisharif, Patna 801507, Bihār, India. arnabmck999@gmail.com
Key Words	Prophylactic zinc; Acute respiratory infections; Diarrhoea; Growth; Routine immunization
Core Tip	This randomized controlled trial evaluated the efficacy of prophylactic intermittent zinc supplementation in reducing acute respiratory infections (ARI) and diarrhoea among infants. The study demonstrated that infants receiving zinc supplementation had a significantly lower incidence of ARI and diarrhoea, as well as greater gains in weight and length, compared to the control group. These findings suggest that intermittent zinc supplementation, administered alongside routine vaccinations, is an effective and low-cost strategy to reduce infant morbidity and mortality from ARI and diarrhoea, and can be feasibly implemented in resource-limited healthcare settings.
Citation	Kumar CM, Ghorui A, Hamsay K. Efficacy of prophylactic intermittent zinc supplementation for reducing acute respiratory infections and diarrhoea in infants: A randomized controlled trial. World J Clin Pediatr 2025; In press

Received	2025-05-06 06:34
Peer-Review Started	2025-05-06 06:35
To Make the First Decision
Return for Revision	2025-05-17 14:54
Revised	2025-05-31 13:49
Second Decision	2025-09-18 02:54
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-09-19 01:30
Articles in Press	2025-09-19 01:30
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	2219-2808 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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