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Publication Name World Journal of Hepatology
Manuscript ID 109118
Country India
Category Gastroenterology & Hepatology
Manuscript Type Minireviews
Article Title Stratification and selection of therapies to improve survival in severe alcoholic hepatitis
Manuscript Source Invited Manuscript
All Author List Ajay Kumar Mishra and Amit Goel
Funding Agency and Grant Number
Corresponding Author Amit Goel, Department of Hepatology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Raebareli Road, Lucknow 226014, Uttar Pradesh, India. agoel.ag@gmail.com
Key Words Severe alcoholic hepatitis; Steroids; Granulocyte colony stimulating factor; Plasma exchange; Faecal microbiota transplantation
Core Tip Clinically, severe alcoholic hepatitis (SAH) presents with jaundice, with or without ascites or encephalopathy, and it progresses rapidly. The patient population is heterogeneous and needs to be stratified according to their eligibility for specific therapies. Emerging alternatives or rescue therapies are available for SAH. The decision for the preferred therapy is based on patient profile, clinical experiences, and its side effects profile. This comprehensive review provides insight into the stratification of patients who need specific therapies, with the primary focus on the therapies that improve survival in SAH.
Citation Mishra AK, Goel A. Stratification and selection of therapies to improve survival in severe alcoholic hepatitis. World J Hepatol 2025; In press
Received
2025-04-30 06:11
Peer-Review Started
2025-04-30 06:12
To Make the First Decision
Return for Revision
2025-05-14 09:22
Revised
2025-05-21 05:18
Second Decision
2025-08-07 02:44
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief
2025-08-08 10:22
Articles in Press
2025-08-08 10:22
Publication Fee Transferred
Edit the Manuscript by Language Editor
2025-08-12 19:51
Typeset the Manuscript
ISSN 1948-5182 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com