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Articles in Press
7/10/2025 7:46:37 AM | Browse: 11 | Download: 0
Category |
Orthopedics |
Manuscript Type |
Editorial |
Article Title |
Advancing bone regeneration: Clinical implications of synthetic biomaterials and fibrin derivatives
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Manuscript Source |
Invited Manuscript |
All Author List |
Ren-Xian Xie, Yi-Xuan Xing and Nian-Zhe Sun |
Funding Agency and Grant Number |
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Corresponding Author |
Nian-Zhe Sun, MD, Department of Orthopedics, Xiangya Hospital, Central South University, No. 87 Xiangya Road, Kaifu District, Changsha 410008, Hunan Province, China. sunnzh201921@sina.com |
Key Words |
Biomaterials; Bone regeneration; Fibrin sealant; Hydroxyapatite; Regenerative medicine |
Core Tip |
The integration of synthetic biomaterials, for example hydroxyapatite and β-tricalcium phosphate, with fibrin derivatives enhances bone regeneration by improving scaffold stability, cellular recruitment, and mechanical support. While promising, clinical adoption requires standardized protocols, long-term outcome validation, and personalized approaches to address complex bone defects in aging and comorbid populations. |
Citation |
Xie RX, Xing YX, Sun NZ. Advancing bone regeneration: Clinical implications of synthetic biomaterials and fibrin derivatives. World J Orthop 2025; In press |
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Received |
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2025-05-06 09:46 |
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Peer-Review Started |
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2025-05-06 09:46 |
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To Make the First Decision |
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Return for Revision |
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2025-06-10 07:14 |
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Revised |
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2025-06-13 02:26 |
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Second Decision |
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2025-07-10 02:44 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2025-07-10 07:46 |
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Articles in Press |
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2025-07-10 07:46 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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ISSN |
2218-5836 (online) |
Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
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