Publication Name	World Journal of Gastrointestinal Surgery
Manuscript ID	109326
Country	Japan

Category	Gastroenterology & Hepatology
Manuscript Type	Retrospective Study
Article Title	Preoperative performance status was associated with postoperative fatal complications in elderly patients with refractory ulcerative colitis
Manuscript Source	Unsolicited Manuscript
All Author List	Yuki Horio, Motoi Uchino, Yusuke Tomoo, Kazunori Nomura, Kentaro Nagano, Kurando Kusunoki, Ryuichi Kuwahara, Kei Kimura, Toshiyuki Sato, Kozo Kataoka, Masataka Igeta, Shinichiro Shinzaki, Masataka Ikeda and Hiroki Ikeuchi
Funding Agency and Grant Number
Corresponding Author	Yuki Horio, Lecturer, Department of Gastroenterological Surgery, Hyogo Medical University, 1-1, Mukogawa-cho, Nishinomiya Hyogo 663-8501, Japan, Nishinomiya 663-8501, Hyogo, Japan. yu-horio@hyo-med.ac.jp
Key Words	Ulcerative colitis; Surgery; Elderly; Postoperative complication; Body mass index; Eastern Cooperative Oncology Group performance status
Core Tip	This study identified low body mass index (< 17 kg/m²) and poor Eastern Cooperative Oncology Group performance status (≥ 3) as independent risk factors for fatal postoperative complications in elderly patients with refractory ulcerative colitis. The most common fatal complication was pneumonia due to disuse syndrome. These findings emphasize the importance of early surgical intervention before significant functional decline or weight loss occurs. In the era of complex biologic therapies, these simple, clinically assessable markers offer practical guidance for timely surgical decision-making in high-risk elderly patients.
Citation	Horio Y, Uchino M, Tomoo Y, Nomura K, Nagano K, Kusunoki K, Kuwahara R, Kimura K, Sato T, Kataoka K, Igeta M, Shinzaki S, Ikeda M, Ikeuchi H. Preoperative performance status was associated with postoperative fatal complications in elderly patients with refractory ulcerative colitis. World J Gastrointest Surg 2025; In press

Received	2025-05-08 06:25
Peer-Review Started	2025-05-08 06:25
To Make the First Decision
Return for Revision	2025-05-14 10:57
Revised	2025-05-19 01:55
Second Decision	2025-06-12 02:42
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-06-12 07:46
Articles in Press	2025-06-12 07:46
Publication Fee Transferred	2025-05-28 00:40
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ISSN	1948-9366 (online)
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