Publication Name	World Journal of Gastrointestinal Surgery
Manuscript ID	109359
Country	China

Category	Gastroenterology & Hepatology
Manuscript Type	Minireviews
Article Title	Cholecystectomy and non-alcoholic fatty liver disease: Exploring the hidden connection and implications
Manuscript Source	Invited Manuscript
All Author List	Xue-Yan Liu, Jing Ma and Yan Jiao
Funding Agency and Grant Number
Corresponding Author	Yan Jiao, Department of Hepatobiliary and Pancreatic Surgery, General Surgery Center, First Hospital of Jilin University, No. 1 Xinmin Street, Changchun 130000, Jilin Province, China. lagelangri1@126.com
Key Words	Cholecystectomy; Non-alcoholic fatty liver disease; Bile acid metabolism; Gut microbiota dysbiosis; Lipid homeostasis; Metabolic syndrome; Liver health
Core Tip	Cholecystectomy, a common surgical treatment for gallbladder diseases, may inadvertently increase the risk of non-alcoholic fatty liver disease due to disrupted bile acid metabolism, gut microbiota dysbiosis, and altered lipid regulation. These metabolic disturbances are especially pronounced in patients with obesity or insulin resistance. This review highlights emerging mechanistic insights and underscores the importance of proactive liver health monitoring and lifestyle intervention following cholecystectomy.
Citation	Liu XY, Ma J, Jiao Y. Cholecystectomy and non-alcoholic fatty liver disease: Exploring the hidden connection and implications. World J Gastrointest Surg 2025; In press

Received	2025-05-09 10:44
Peer-Review Started	2025-05-09 10:44
To Make the First Decision
Return for Revision	2025-05-27 08:39
Revised	2025-05-27 14:15
Second Decision	2025-09-04 02:49
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-09-04 06:12
Articles in Press	2025-09-04 06:12
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1948-9366 (online)
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