BPG is committed to discovery and dissemination of knowledge
Articles in Press
7/10/2025 3:14:11 AM | Browse: 17 | Download: 0
Category |
Urology & Nephrology |
Manuscript Type |
Case Report |
Article Title |
Avacopan in the treatment of relapsing polychondritis with myeloperoxidase-antineutrophil cytoplasmic antibody associated vasculitis: A case report
|
Manuscript Source |
Unsolicited Manuscript |
All Author List |
Jack Tang Nguyen and Manish Anand |
Funding Agency and Grant Number |
|
Corresponding Author |
Jack Tang Nguyen, Doctorate Student, College of Medicine, University of Cincinnati, 3230 Eden Ave, Cincinnati, OH 45220, United States. nguyenjack91801@gmail.com |
Key Words |
Antineutrophil cytoplasmic antibody; Polychondritis; Vasculitis; Myeloperoxidase-antineutrophil cytoplasmic antibody; Case report |
Core Tip |
This case report presents a rare overlap of relapsing polychondritis and myeloperoxidase anti-neutrophil cytoplasmic antibody associated vasculitis, complicated by severe acute kidney injury. The patient demonstrated sustained renal improvement following treatment with Avacopan, a complement 5a receptor antagonist, after intolerance to rituximab. This case highlights the potential role of Avacopan in preserving renal function and achieving disease control in complex autoimmune syndromes, especially when conventional immunosuppressive regimens are contraindicated or poorly tolerated. |
Citation |
Nguyen JT, Anand M. Avacopan in the treatment of relapsing polychondritis with myeloperoxidase-antineutrophil cytoplasmic antibody associated vasculitis: A case report. World J Nephrol 2025; In press |
 |
Received |
|
2025-05-12 02:59 |
 |
Peer-Review Started |
|
2025-05-13 08:46 |
 |
To Make the First Decision |
|
|
 |
Return for Revision |
|
2025-05-23 11:27 |
 |
Revised |
|
2025-05-28 01:07 |
 |
Second Decision |
|
2025-07-10 02:46 |
 |
Accepted by Journal Editor-in-Chief |
|
|
 |
Accepted by Executive Editor-in-Chief |
|
2025-07-10 03:14 |
 |
Articles in Press |
|
2025-07-10 03:14 |
 |
Publication Fee Transferred |
|
2025-05-29 18:22 |
 |
Edit the Manuscript by Language Editor |
|
|
 |
Typeset the Manuscript |
|
|
ISSN |
2220-6124 (online) |
Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
Copyright |
©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
|
Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
© 2004-2025 Baishideng Publishing Group Inc. All rights reserved. 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
California Corporate Number: 3537345