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Articles in Press
7/31/2025 8:31:09 AM | Browse: 122 | Download: 0
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Letter to the Editor |
| Article Title |
Interleukin-36 subfamily cytokines in liver diseases
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Zhe-Kun Xiong, Si-Min Gu and Yi-Yuan Zheng |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| National Natural Science Foundation of China |
82104549 |
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| Corresponding Author |
Yi-Yuan Zheng, Department of Gastroenterology, Shanghai Municipal Hospital of Traditional Chinese Medicine, No. 274 Zhijiang Middle Road, Shanghai 200071, China. iceroser@126.com |
| Key Words |
Interleukin-36; Inflammation; Macrophages; T cells; Liver cirrhosis; Metabolic dysfunction-associated liver disease; Gut microbiota |
| Core Tip |
This letter discusses the important role of the interleukin-36 (IL-36) subfamily in the pathogenesis of liver diseases, particularly in modulating immune responses and promoting inflammation. Although considerable knowledge gaps remain regarding the precise mechanisms through which IL-36 cytokines contribute to liver damage, emerging evidence suggests that the targeting of IL-36 signaling may present novel therapeutic avenues for the management of chronic liver diseases. Further research is essential to investigate the potential of IL-36 as both a biomarker and a therapeutic target within clinical contexts. |
| Citation |
Xiong ZK, Gu SM, Zheng YY. Interleukin-36 subfamily cytokines in liver diseases. World J Hepatol 2025; 17(9): 109429 |
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Received |
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2025-05-12 03:37 |
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Peer-Review Started |
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2025-05-12 08:49 |
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First Decision by Editorial Office Director |
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2025-05-29 08:53 |
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Return for Revision |
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2025-05-29 08:53 |
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Revised |
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2025-06-06 08:05 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2025-07-31 02:40 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2025-07-31 08:31 |
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Articles in Press |
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2025-07-31 08:31 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2025-09-12 08:30 |
| ISSN |
1948-5182 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
|
| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
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