Publication Name	World Journal of Gastroenterology
Manuscript ID	109468
Country	United Kingdom

Category	Endocrinology & Metabolism
Manuscript Type	Editorial
Article Title	Duodenal mucosal ablation: An emerging therapeutic concept for metabolic dysfunction-associated fatty liver disease
Manuscript Source	Invited Manuscript
All Author List	Cornelius J Fernandez, Sweekruti Jena, Vijaya Lakshmi and Joseph M Pappachan
Funding Agency and Grant Number
Corresponding Author	Joseph M Pappachan, Academic Editor, FRCP, MD, MRCP, Professor, Senior Researcher, Faculty of Science, Manchester Metropolitan University, All Saints Building, Oxford Road, Manchester M15 6BH, United Kingdom. drpappachan@yahoo.co.in
Key Words	Duodenal mucosal ablation; Endoscopic bariatric procedure; Type 2 diabetes mellitus; Metabolic and bariatric surgery; Obesity; Hepatic steatosis; Metabolic dysfunction-associated fatty liver disease
Core Tip	Metabolic dysfunction-associated fatty liver disease is recognized as the most common cause of chronic liver disease globally with obesity being the prime driver for insulin resistance and hepatic steatosis. Though metabolic and bariatric surgery (MBS) is the most effective treatment option for severe obesity, it carries complication risks and long-term commitment to lifestyle adjustments. In the evolving landscape of obesity management, minimally invasive endoscopic bariatric therapies offer promising weight loss and metabolic benefits with lower complication rates compared to MBS. This editorial provides a comprehensive overview of various endoscopic bariatric techniques used in management of obesity and their effect on metabolic dysfunction-associated fatty liver disease which will help physicians to offer safer alternatives to conventional MBS.
Citation	Fernandez CJ, Jena S, Lakshmi V, Pappachan JM. Duodenal mucosal ablation: An emerging therapeutic concept for metabolic dysfunction-associated fatty liver disease. World J Gastroenterol 2025; In press

Received	2025-05-12 12:55
Peer-Review Started	2025-05-12 12:56
To Make the First Decision
Return for Revision	2025-05-26 20:39
Revised	2025-05-30 17:39
Second Decision	2025-07-03 02:41
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-07-03 06:15
Articles in Press	2025-07-03 06:15
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1007-9327 (print) and 2219-2840 (online)
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