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Articles in Press
9/22/2025 9:32:40 AM | Browse: 58 | Download: 0
Category |
Psychiatry |
Manuscript Type |
Minireviews |
Article Title |
Agitation in Alzheimer’s disease: From assessment to therapeutics
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Manuscript Source |
Invited Manuscript |
All Author List |
Antonio L Teixeira, Youngran Kim, Thiago M Cordeiro, Gabriel A de Erausquin and Natalia P Rocha |
Funding Agency and Grant Number |
Funding Agency |
Grant Number |
National Institutes of Health/National Institute on Aging |
No. 1R21AG091282 |
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Corresponding Author |
Antonio L Teixeira, Biggs Institute, The University of Texas Health Science Center at San Antonio, 8300 Floyd Curl Drive, San Antonio, TX 78229, United States. altexr@gmail.com |
Key Words |
Alzheimer’s disease; Dementia; Agitation; Aggression; Antipsychotics; Antidepressants |
Core Tip |
In Alzheimer’s disease, agitation is a clinically relevant neuropsychiatric syndrome managed by non-pharmacological and pharmacological approaches. Ruling out delirium, identifying and addressing environmental triggers (e.g., change in caregiver) are fundamental therapeutic steps. Antipsychotics (e.g., brexpiprazole, risperidone) are commonly used in acute agitation, especially in the context of potential harm to self and others. For chronic agitation, serotonin-selective reuptake inhibitors (e.g., escitalopram) are preferred. |
Citation |
Teixeira AL, Kim Y, Cordeiro TM, de Erausquin GA, Rocha NP. Agitation in Alzheimer’s disease: From assessment to therapeutics. World J Psychiatry 2025; In press |
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Received |
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2025-05-15 01:49 |
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Peer-Review Started |
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2025-05-26 00:08 |
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To Make the First Decision |
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Return for Revision |
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2025-05-29 08:16 |
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Revised |
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2025-06-09 20:08 |
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Second Decision |
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2025-09-22 02:41 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2025-09-22 09:32 |
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Articles in Press |
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2025-09-22 09:32 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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ISSN |
2220-3206 (online) |
Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
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