Publication Name	World Journal of Hepatology
Manuscript ID	109807
Country	Egypt

Category	Physiology
Manuscript Type	Basic Study
Article Title	Ginger mitigates acrylamide-induced hepatotoxicity through antioxidant and anti-inflammatory mechanisms in rats
Manuscript Source	Unsolicited Manuscript
All Author List	Ahmed El-Sayed Nour El Deen, Fatma Rashed, Amira Osman, Osama Khalil Farag, Ahmed F Abdel Ghany, Almoatazbellah Mahmoud Elsayed, Sherif M A Mansour, Mohammed Abdel Aziz Mohammed, Reda S Taha, Sami Ahmed Zaher Basha, Mostafa Mahmoud Youssef Mohamed and Ahmad Taha
Funding Agency and Grant Number
Corresponding Author	Ahmed El-Sayed Nour El Deen, Professor, Department of Physiology, Faculty of Medicine, Al-Azhar University, Grees, Assuit 002, Egypt. a.nourelden@zu.edu.jo
Key Words	Acrylamide; Ginger; Hepatotoxicity; Antioxidants; Oxidative
Core Tip	Acrylamide (ACR), a common toxin in processed foods, poses serious risks to liver health through oxidative stress and inflammation. This study tested whether ginger extract could protect the liver against ACR damage in rats. The results showed that ginger significantly improved liver function, reduced oxidative damage, and supported antioxidant defenses. These findings suggest that ginger may serve as a natural and accessible dietary strategy to protect the liver from toxins found in everyday food. This research highlights the potential of ginger as a safe supplement to prevent food-related liver injury.
Citation	Nour El Deen AES, Rashed F, Osman A, Khalil Farag O, Abdel Ghany AF, Elsayed AM, Mansour SMA, Mohammed MAA, Taha RS, Basha SAZ, Mohamed MMY, Taha A. Ginger mitigates acrylamide-induced hepatotoxicity through antioxidant and anti-inflammatory mechanisms in rats. World J Hepatol 2025; In press

Received	2025-05-22 09:10
Peer-Review Started	2025-05-22 09:20
To Make the First Decision
Return for Revision	2025-06-13 03:24
Revised	2025-07-03 05:17
Second Decision	2025-09-04 02:51
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-09-04 06:05
Articles in Press	2025-09-04 06:05
Publication Fee Transferred	2025-08-11 16:20
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1948-5182 (online)
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