Publication Name	World Journal of Gastrointestinal Surgery
Manuscript ID	109920
Country	China

Category	Surgery
Manuscript Type	Case Report
Article Title	Transanal intersphincteric approach combined with Kangfuxin enema for treating anastomotic leakage after low anterior resection: Three case reports
Manuscript Source	Unsolicited Manuscript
All Author List	Hui Li, Hai-Bin Huang, Tao Xiang, Lu Yang, Eedgar J B Furnée, Ge Sun and Wen-Bin Chen
Funding Agency and Grant Number	Funding Agency Grant Number Zhejiang Provincial Basic Public Welfare Research Program No. LZ21H160004
Corresponding Author	Wen-Bin Chen, Director, MD, Department of Colorectal Surgery, The First Affiliated Hospital, Zhejiang University School of Medicine, No. 79 Qingchun Road, Hangzhou 310003, Zhejiang Province, China. wenbinchen@zju.edu.cn
Key Words	Low rectal cancer; Anastomotic leakage; Transanal opening of the intersphincteric space; Kangfuxin liquid; Enema therapy; Case report
Core Tip	This case series presents a novel, minimally invasive strategy for managing anastomotic leakage following low anterior resection for rectal cancer. By combining the transanal opening of the intersphincteric space technique with Kangfuxin liquid enemas, all three patients achieved complete healing with preserved anal function. This approach specifically targets leaks confined to the intersphincteric space and may serve as an effective adjunct to conventional protective measures, potentially enhancing patient outcomes and accelerating recovery.
Citation	Li H, Huang HB, Xiang T, Yang L, Furnée EJB, Sun G, Chen WB. Transanal intersphincteric approach combined with Kangfuxin enema for treating anastomotic leakage after low anterior resection: Three case reports. World J Gastrointest Surg 2025; In press

Received	2025-05-26 06:46
Peer-Review Started	2025-05-26 06:48
To Make the First Decision
Return for Revision	2025-05-28 09:41
Revised	2025-06-29 04:45
Second Decision	2025-09-04 02:48
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-09-04 05:36
Articles in Press	2025-09-04 05:36
Publication Fee Transferred	2025-07-03 14:38
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1948-9366 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright	© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com