Publication Name	World Journal of Hepatology
Manuscript ID	110029
Country	China

Category	Oncology
Manuscript Type	Case Report
Article Title	Unusual presentation of synchronous double primary gallbladder and hepatic malignancies: A case report
Manuscript Source	Invited Manuscript
All Author List	Kun Zhang and Hong-Liang Liu
Funding Agency and Grant Number
Corresponding Author	Hong-Liang Liu, Professor, Department of Hepatobiliary Surgery, Qingdao Women and Children’s Hospital, No. 6 Tongfu Road, Qing Dao 266000, Shandong, China. 1715069155@qq.com
Key Words	Multiple primary cancers; Metastatic cancer; Multidisciplinary team; Diagnosis and treatment; Prognosis; Case report
Core Tip	The synchronous double primary malignancies of the gallbladder and liver represent an exceedingly rare clinical entity with no established management consensus. We present a distinctive case of a 70-year-old patient who achieved no evidence of disease status following multidisciplinary intervention. This case highlights the diagnostic challenges in distinguishing synchronous primaries from metastatic disease, underscores the critical role of histopathological confirmation, and demonstrates the potential for favorable outcomes through aggressive surgical intervention. Our experience provides valuable insights for managing such complex cases.
Citation	Zhang K, Liu HL. Unusual presentation of synchronous double primary gallbladder and hepatic malignancies: A case report. World J Hepatol 2025; In press

Received	2025-06-03 07:05
Peer-Review Started	2025-06-03 07:07
To Make the First Decision
Return for Revision	2025-06-26 07:51
Revised	2025-07-29 15:23
Second Decision	2025-09-29 02:34
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-09-29 06:04
Articles in Press	2025-09-29 06:04
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1948-5182 (online)
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