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Publication Name World Journal of Radiology
Manuscript ID 110048
Country China
Category Gastroenterology & Hepatology
Manuscript Type Editorial
Article Title Radiomics for preoperative pancreatic ductal adenocarcinoma risk stratification: Cross-population validation, multidimensional integration, challenges, and future directions
Manuscript Source Invited Manuscript
All Author List Qin-Zhi Liu, Lei Zeng and Nian-Zhe Sun
Funding Agency and Grant Number
Corresponding Author Nian-Zhe Sun, MD, National Clinical Research Center of Geriatric Disorders, Department of Orthopedics, Xiangya Hospital, Central South University, No. 87 Xiangya Road, Kaifu District, Changsha 410008, Hunan Province, China. sunnzh201921@sina.com
Key Words Pancreatic ductal adenocarcinoma; Postoperative recurrence; Risk assessment system; Preoperative assessment; Radiomics
Core Tip This editorial critically evaluated the retrospective study by Liu et al in validating a preoperative computed tomography-based risk scoring system, while high-lighting the potential of radiomics integrated with machine learning for multimodal data analysis. However, clinical translation continues to face significant challenges, including heterogeneity in imaging parameters, incomplete elucidation of molecular mechanisms, and confounding effects of therapeutic interventions. Future research should prioritize the development of multidimensional predictive frameworks that synergize radiological, molecular, and clinical data. Prospective clinical trials to validate model efficacy and artificial intelligence-driven real-time risk stratification systems represent critical initiatives to overcome current limitations in precision medicine implementation, thereby advancing personalized management strategies for pancreatic ductal adenocarcinoma.
Citation Liu QZ, Zeng L, Sun NZ. Radiomics for preoperative pancreatic ductal adenocarcinoma risk stratification: Cross-population validation, multidimensional integration, challenges, and future directions. World J Radiol 2025; In press
Received
2025-05-28 09:51
Peer-Review Started
2025-05-28 09:51
To Make the First Decision
Return for Revision
2025-06-06 03:35
Revised
2025-06-09 10:16
Second Decision
2025-07-10 02:44
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief
2025-07-10 07:35
Articles in Press
2025-07-10 07:35
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
ISSN 1949-8470 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
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