Publication Name	World Journal of Hepatology
Manuscript ID	110128
Country	Saudi Arabia

Category	Gastroenterology & Hepatology
Manuscript Type	Letter to the Editor
Article Title	Gender disparities in hepatitis C treatment: A call for tailored approaches
Manuscript Source	Invited Manuscript
All Author List	Eyad Gadour
Funding Agency and Grant Number
Corresponding Author	Eyad Gadour, CCST, Consultant, FACP, FRCP, MRCP, Professor, Multiorgan Transplant Centre of Excellence, Liver Transplantation Unit, King Fahad Specialist Hospital, Ammar Bin Thabit Street, Dammam 32253, Saudi Arabia. eyadgadour@doctors.org.uk
Key Words	Gender disparities; Hepatitis C treatment; Sustained virologic response; Menopausal status; Personalized care
Core Tip	Recent research has revealed significant sex disparities in hepatitis C treatment outcomes. Women, particularly premenopausal and menopausal women, show higher sustained virologic response rates than men. However, postmenopausal women face unique challenges. This highlights the need for sex-sensitive approaches in hepatitis C management, considering biological, hormonal, and psychosocial factors. Healthcare providers should implement tailored treatment strategies to address such disparities, improve patient outcomes, and ensure equitable care. Further research is needed to explore the underlying mechanisms driving these differences, ultimately contributing to more effective and personalized care across diverse demographics.
Citation	Gadour E. Gender disparities in hepatitis C treatment: A call for tailored approaches. World J Hepatol 2025; In press

Received	2025-05-30 01:39
Peer-Review Started	2025-05-30 03:08
To Make the First Decision
Return for Revision	2025-06-06 03:34
Revised	2025-06-15 06:07
Second Decision	2025-08-04 02:52
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-08-04 11:48
Articles in Press	2025-08-04 11:48
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1948-5182 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
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