Publication Name	World Journal of Cardiology
Manuscript ID	110278
Country	China

Category	Medical Laboratory Technology
Manuscript Type	Retrospective Cohort Study
Article Title	Correlation of APOE, SLCO1B1 and LPA KIV-2 gene polymorphisms with coronary heart disease in the Teochew population
Manuscript Source	Unsolicited Manuscript
All Author List	Jia-Xin Xu, Ye Wu, Lin Zhang, Yong-Hao Wu, Chun-Lai Li and Fen Lin
Funding Agency and Grant Number	Funding Agency Grant Number Special Research Plan 2023 of Chaozhou 202303GY05
Corresponding Author	Fen Lin, Chief, Professor, Precision Medical Lab Center, Chaozhou Central Hospital, No. 99 Dongshan Road, Chaozhou 521000, Guangdong Province, China. 26395868@qq.com
Key Words	Gene polymorphisms; Coronary heart disease; Teochew population; APOE; SLCO1B1; KIV-2
Core Tip	In this study of 324 patients with coronary heart disease (CHD) and 143 control participants, we analysed polymorphisms in the APOE and SLCO1B1 genes, as well as LPA KIV-2 copy number variation in the Teochew population of southern China. We confirmed that both APOE ɛ2 allele and higher KIV-2 copy number are associated with a reduced risk of CHD in the Teochew population, whereas neither the APOE ɛ4 allele nor SLCO1B1 gene showed any association.
Citation	Xu JX, Wu Y, Zhang L, Wu YH, Li CL, Lin F. Correlation of APOE, SLCO1B1 and LPA KIV-2 gene polymorphisms with coronary heart disease in the Teochew population. World J Cardiol 2025; In press

Received	2025-06-11 10:35
Peer-Review Started	2025-06-11 10:35
To Make the First Decision
Return for Revision	2025-06-17 07:51
Revised	2025-06-25 13:26
Second Decision	2025-08-11 02:52
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-08-11 10:19
Articles in Press	2025-08-11 10:19
Publication Fee Transferred	2025-06-27 02:48
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1949-8462 (online)
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