Publication Name	World Journal of Gastrointestinal Pharmacology and Therapeutics
Manuscript ID	110305
Country	China

Category	Microbiology
Manuscript Type	Letter to the Editor
Article Title	Microbiome-derived metabolites in cancer-associated anemia: An underexplored mechanistic link
Manuscript Source	Unsolicited Manuscript
All Author List	Zhe Wang and Feng Wang
Funding Agency and Grant Number
Corresponding Author	Feng Wang, MD, PhD, Professor, Senior Researcher, Senior Scientist, Department of Oncology, The First Affiliated Hospital of Zhengzhou University, No. 50 Eastern Jianshe Road, Zhengzhou 450052, Henan Province, China. zzuwangfeng@zzu.edu.cn
Key Words	Cancer-associated anemia; Gut microbiota; Microbial metabolites; Short-chain fatty acids; Tryptophan; Aryl hydrocarbon receptor
Core Tip	Microbial metabolites—including short-chain fatty acids and tryptophan-derived ligands of the aryl hydrocarbon receptor—modulate erythropoiesis and iron metabolism. This commentary underscores the need to integrate microbial metabolite biology into future research on cancer-associated anemia.
Citation	Wang Z, Wang F. Microbiome-derived metabolites in cancer-associated anemia: An underexplored mechanistic link. World J Gastrointest Pharmacol Ther 2025; In press

Received	2025-06-04 03:38
Peer-Review Started	2025-06-04 03:43
To Make the First Decision
Return for Revision	2025-06-07 06:05
Revised	2025-06-09 07:44
Second Decision	2025-07-14 02:41
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-07-15 00:47
Articles in Press	2025-07-15 00:47
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	2150-5349 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com