Publication Name	World Journal of Gastrointestinal Oncology
Manuscript ID	110415
Country	Japan

Category	Gastroenterology & Hepatology
Manuscript Type	Minireviews
Article Title	Current insights and future perspectives of treatment strategies for biliary tract cancer
Manuscript Source	Invited Manuscript
All Author List	Kei Nakagawa, Shingo Tsujinaka, Yu Katayose, Kenichiro Yambe, Hiroto Sakurai, Kazuhiro Takami, Noriko Kondo, Kuniharu Yamamoto and Chikashi Shibata
Funding Agency and Grant Number
Corresponding Author	Kei Nakagawa, Associate Professor, MD, Division of Hepato-Biliary and Pancreatic Surgery, Department of Surgery, Tohoku Medical and Pharmaceutical University, 1-15-1 Fukumuro, Miyagino-ku, Sendai 983-8536, Miyagi, Japan. nakagawa.kei@tohoku-mpu.ac.jp
Key Words	Biliary tract cancer; Surgical indication; Immune checkpoint inhibitor; Molecular targeted drug; Fibroblast growth factor receptor
Core Tip	Radical resection is an important treatment for biliary tract cancer (BTC). However, radical resection for hilar cholangiocarcinoma is associated with a high incidence of complications and mortality. Preoperative assessment of the resectability and meticulous perioperative management are essential. Adjuvant chemotherapy has recently been developed for cases that are deemed unresectable. Additionally, immune checkpoint inhibitors and molecular-target agents are recent additions to the treatment options. Improvements in the overall treatment outcomes for BTC are expected. A multidisciplinary treatment strategy centered on surgical treatment of BTC will contribute to more successful outcomes.
Citation	Nakagawa K, Tsujinaka S, Katayose Y, Yambe K, Sakurai H, Takami K, Kondo N, Yamamoto K, Shibata C. Current insights and future perspectives of treatment strategies for biliary tract cancer. World J Gastrointest Oncol 2025; In press

Received	2025-06-06 17:04
Peer-Review Started	2025-06-06 17:04
To Make the First Decision
Return for Revision	2025-06-17 12:07
Revised	2025-06-29 10:29
Second Decision	2025-08-26 02:38
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-08-26 06:51
Articles in Press	2025-08-26 06:51
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1948-5204 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright	© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com