Publication Name	World Journal of Transplantation
Manuscript ID	110496
Country	Mexico

Category	Gastroenterology & Hepatology
Manuscript Type	Minireviews
Article Title	Overcoming barriers and expanding opportunities in liver transplantation in Mexico
Manuscript Source	Invited Manuscript
All Author List	Jose Alonso Avila-Rojo, Froylan David Martínez-Sánchez, Luis Alejandro Rosales-Rentería, David Aguirre-Villarreal, Alan G Contreras, Rodrigo Cruz-Martinez, Maximiliano Servin-Rojas, Alejandro Ramírez-del Val, Daniel Zamora-Valdés, Pilar Leal-Leyte, Jonathan Aguirre-Valadez, Victor Manuel Paez-Zayas, Aczel I Sánchez-Cedillo, Alejandro Lugo-Baruqui, Joshue David Covarrubias-Esquer, Francisco I García-Juárez, Isaac Ruiz and Ignacio García-Juárez
Funding Agency and Grant Number
Corresponding Author	Ignacio García-Juárez, MD, Professor, Department of Gastroenterology and Hepatology, Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran, Avenue Vasco de Quiroga 15, Belisario Domínguez Secc 16, Mexico City 14080, Ciudad de Mexico, Mexico. drinter77@gmail.com
Key Words	Liver transplantation; Organ donation; Mexico; Hepatitis C virus; Perfusion; Health systems; Health services accessibility
Core Tip	Liver transplantation in Mexico remains disproportionately concentrated in a few urban centers and significantly lags behind regional benchmarks. This mini-review highlights the historical development of the transplant system, ongoing challenges such as low donor rates and fragmented healthcare structures, and opportunities for innovation through donation after circulatory death protocols, hepatitis C virus-positive graft utilization, and machine perfusion strategies. Implementing national reforms could bridge the gap between transplant capacity and patient need.
Citation	Avila-Rojo JA, Martínez-Sánchez FD, Rosales-Rentería LA, Aguirre-Villarreal D, Contreras AG, Cruz-Martinez R, Servin-Rojas M, Ramírez-del Val A, Zamora-Valdés D, Leal-Leyte P, Aguirre-Valadez J, Paez-Zayas VM, Sánchez-Cedillo AI, Lugo-Baruqui A, Covarrubias-Esquer JD, García-Juárez FI, Ruiz I, García-Juárez I. Overcoming barriers and expanding opportunities in liver transplantation in Mexico. World J Transplant 2025; In press

Received	2025-06-09 08:10
Peer-Review Started	2025-06-09 08:11
To Make the First Decision
Return for Revision	2025-06-17 09:27
Revised	2025-06-18 00:16
Second Decision	2025-09-12 02:40
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-09-12 09:31
Articles in Press	2025-09-12 09:31
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	2220-3230 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
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