Publication Name	World Journal of Gastrointestinal Surgery
Manuscript ID	110644
Country	Bosnia and Herzegovina

Category	Gastroenterology & Hepatology
Manuscript Type	Editorial
Article Title	Optimal timing of pyogenic liver abscess evacuation: The role of early ultrasound-guided intervention
Manuscript Source	Invited Manuscript
All Author List	Enver Zerem, Predrag Jovanovic, Suad Kunosic, Admir Kurtcehajic, Dina Zerem and Omar Zerem
Funding Agency and Grant Number
Corresponding Author	Enver Zerem, Full Professor, MD, PhD, Department of Medical Sciences, The Academy of Sciences and Arts of Bosnia and Herzegovina, Bistrik 7, Sarajevo 71000, Bosnia and Herzegovina. zerem@live.com
Key Words	Pyogenic liver abscess; Ultrasound-guided drainage; Early intervention; Minimally invasive surgery; Image-guided procedures; Hepatobiliary infection; Clinical management; Percutaneous drainage
Core Tip	Timely and individualized treatment of pyogenic liver abscess is essential for optimal outcomes and complication prevention. This editorial highlighted ultrasound (US)-guided procedures as safe, effective, and minimally invasive therapeutic strategies. Emerging evidence supports early US-guided interventions - even in partially or non-liquefied abscesses - challenging the traditional preference for delayed drainage. Needle aspiration is particularly suited for smaller or multiloculated abscesses, as it avoids unnecessary catheter placement and reduces procedural risks. Tailoring US-guided interventions to abscess characteristics and the patient’s clinical status is key to successful management of pyogenic liver abscess.
Citation	Zerem E, Jovanovic P, Kunosic S, Kurtcehajic A, Zerem D, Zerem O. Optimal timing of pyogenic liver abscess evacuation: The role of early ultrasound-guided intervention. World J Gastrointest Surg 2025; In press

Received	2025-06-12 03:50
Peer-Review Started	2025-06-12 03:50
To Make the First Decision
Return for Revision	2025-06-25 02:46
Revised	2025-06-29 18:32
Second Decision	2025-09-12 02:38
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-09-12 06:21
Articles in Press	2025-09-12 06:21
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1948-9366 (online)
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