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Publication Name World Journal of Gastroenterology
Manuscript ID 110645
Country China
Category Surgery
Manuscript Type Case Report
Article Title Immunoglobulin G4-related disease requiring clinical attention: A case report and review of literature
Manuscript Source Unsolicited Manuscript
All Author List Ming-Li Yin, Guo-Dong Ma, Yan-Qing Gan, Peng Li, Zai-Dong Zhang, Shu-Bin Zhang, Qiang Meng, Biao Liu and Shou-Ye Zhao
Funding Agency and Grant Number
Funding Agency Grant Number
National Natural Science Foundation of Shandong Province No. ZR2019QH008
Corresponding Author Shou-Ye Zhao, Department of Hepatobiliary Surgery, Affiliated Hospital of Jining Medical University, Jining Medical University, No. 89 Guhuai Road, Jining 272000, Shandong Province, China. zhaoshouye@mail.jnmc.edu.cn
Key Words Immunoglobulin G4; Cholecystitis; Fibrosis; Immune responses; Multidisciplinary treatment; Immunity; Signaling pathway; Glucocorticoids; Gallbladder carcinoma; Case report
Core Tip This article describes a case of immunoglobulin G4 (IgG4)-related cholecystitis (IgG4-CC) in a patient who presented solely with abdominal pain, no pancreatic or biliary duct involvement was evident. Such an isolated occurrence of IgG4-CC is rare because IgG4-CC represents only one manifestation of IgG4-related disease (IgG4-RD). The clinical presentation of IgG4-RD is complex and highly variable, potentially affecting single or multiple organs and tissues, which increases the risks of misdiagnosis and missed diagnosis in clinical practice. For hepatobiliary and pancreatic surgeons, greater awareness of IgG4-RD is essential to avoid unnecessary surgical interventions.
Citation

Yin ML, Ma GD, Gan YQ, Li P, Zhang ZD, Zhang SB, Meng Q, Liu B, Zhao SY. Immunoglobulin G4-related disease requiring clinical attention: A case report and review of literature. World J Gastroenterol 2025; 31(38): 110645

Received
2025-06-24 09:09
Peer-Review Started
2025-06-24 09:09
First Decision by Editorial Office Director
2025-07-14 08:55
Return for Revision
2025-07-14 08:55
Revised
2025-07-27 22:12
Publication Fee Transferred
2025-07-29 14:35
Second Decision by Editor
2025-09-03 02:46
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2025-09-03 06:50
Articles in Press
2025-09-03 06:50
Edit the Manuscript by Language Editor
Typeset the Manuscript
2025-09-23 02:43
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
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