Publication Name	World Journal of Critical Care Medicine
Manuscript ID	110669
Country	Viet Nam

Category	Critical Care Medicine
Manuscript Type	Observational Study
Article Title	Optic nerve sheath diameter trajectories and mortality in children with clinically relevant elevated intracranial pressure
Manuscript Source	Invited Manuscript
All Author List	Dat Minh-Tan Truong, Minh Hoang-Nhat Nguyen, Huy Quang Nguyen, Luan Thanh Vo and Thanh Tat Nguyen
Funding Agency and Grant Number
Corresponding Author	Thanh Tat Nguyen, MD, PhD, Department of Tuberculosis and Epidemiology, Woolcock Institute of Medical Research, Pham Ngoc Thach, Ho Chi Minh City 700000, Viet Nam. thanhhonor@gmail.com
Key Words	Glasgow coma scale; Intracranial pressure; Mortality; Optic nerve sheath diameter; Pediatric intensive care unit
Core Tip	The in-hospital mortality rate in children hospitalized with clinically relevant raised intracranial pressure was 23.2%. Nonsurvivors had a median 5.3% increase in ultrasound-measured optic nerve sheath diameter (ONSD), whereas survivors showed median 5.6% reduction during the first 48 hours of admission. Early changes in ONSD, as measured by ultrasound during the first 48 hours of admission, were strongly correlated with neurological deterioration and mortality risk.
Citation	Truong DMT, Nguyen MHN, Nguyen HQ, Vo LT, Nguyen TT. Optic nerve sheath diameter trajectories and mortality in children with clinically relevant elevated intracranial pressure. World J Crit Care Med 2025; In press

Received	2025-06-12 08:21
Peer-Review Started	2025-06-12 08:21
To Make the First Decision
Return for Revision	2025-06-25 09:29
Revised	2025-07-01 09:21
Second Decision	2025-09-24 02:43
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-09-24 08:43
Articles in Press	2025-09-24 08:43
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	2220-3141(online)
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