Publication Name	World Journal of Hepatology
Manuscript ID	110849
Country	South Korea

Category	Gastroenterology & Hepatology
Manuscript Type	Case Control Study
Article Title	Improved clinical outcomes following embolization of extrahepatic portosystemic shunts in cirrhotic patients with recurrent hepatic encephalopathy
Manuscript Source	Unsolicited Manuscript
All Author List	Jong Won Park, Yook Kim, Jun Su Lee, Il Soon Jung, Ki Bae Kim and Hee Bok Chae
Funding Agency and Grant Number
Corresponding Author	Hee Bok Chae, MD, PhD, Professor, Department of Internal Medicine, Chungbuk National University, College of Medicine and Medical Research Institute, No. 776, 1 Sunhwan-ro, Seowon-gu, Cheongju 28644, Chungbuk, South Korea. hbchae@chungbuk.ac.kr
Key Words	Liver cirrhosis; Hepatic encephalopathy; Extrahepatic portosystemic shunt; Embolization; Survival; Recurrence
Core Tip	Extrahepatic portosystemic shunt (EHPSS) is an underrecognized contributor to hepatic encephalopathy (HE) recurrence and mortality in patients with cirrhosis. In this study, EHPSS embolization significantly improved 1-year survival (50% vs 33%) and prevented HE recurrence (100% vs 17%) compared with no intervention. Embolization also extended both survival and recurrence-free duration. These findings highlight the importance of routine abdominal computed tomography for early EHPSS detection and timely embolization to improve outcomes in cirrhotic patients with recurrent HE.
Citation	Park JW, Kim Y, Lee JS, Jung IS, Kim KB, Chae HB. Improved clinical outcomes following embolization of extrahepatic portosystemic shunts in cirrhotic patients with recurrent hepatic encephalopathy. World J Hepatol 2025; In press

Received	2025-06-17 10:31
Peer-Review Started	2025-06-17 10:31
To Make the First Decision
Return for Revision	2025-06-28 13:26
Revised	2025-07-11 14:08
Second Decision	2025-09-18 02:50
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-09-18 10:21
Articles in Press	2025-09-18 10:21
Publication Fee Transferred	2025-07-12 14:40
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1948-5182 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright	© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com