Publication Name	World Journal of Transplantation
Manuscript ID	110957
Country	United States

Category	Transplantation
Manuscript Type	Retrospective Cohort Study
Article Title	Increased risk of rejection in liver transplant recipients with a history of malabsorptive bariatric surgery
Manuscript Source	Unsolicited Manuscript
All Author List	Jai-Mie Chang, Stephanie Trautmann, Abbigale Hampton, Edie Chan and Nathalie Sela
Funding Agency and Grant Number
Corresponding Author	Jai-Mie Chang, MD, Researcher, Department of General Surgery, Rush University Medical Center, 1750 West Harrison Street, Jelke Suite 769, Chicago, IL 60612, United States. jaimie_chang@rush.edu
Key Words	Liver transplantation; Acute cellular rejection; Malabsorption; Bariatric surgery; Roux-en-Y gastric bypass; Duodenal switch
Core Tip	This study compares perioperative outcomes and episodes of acute cellular rejection between liver transplant recipients with a history of malabsorptive bariatric surgery and controls. Patients with malabsorptive anatomy have higher rates, frequency, and earlier rejection, but no differences in perioperative or 1 year survival outcomes. The mechanism of increased acute cellular rejection is unknown but may be due to altered drug absorption following intestinal bypass. Therefore, this cohort may require meticulous drug-level monitoring or specified postoperative protocols to reduce rejection risk.
Citation	Chang JM, Trautmann S, Hampton A, Chan E, Sela N. Increased risk of rejection in liver transplant recipients with a history of malabsorptive bariatric surgery. World J Transplant 2025; In press

Received	2025-06-19 07:09
Peer-Review Started	2025-06-19 07:10
To Make the First Decision
Return for Revision	2025-07-08 09:36
Revised	2025-07-28 20:59
Second Decision	2025-09-19 02:44
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-09-19 07:59
Articles in Press	2025-09-19 07:59
Publication Fee Transferred	2025-08-08 02:55
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	2220-3230 (online)
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