Publication Name	World Journal of Gastroenterology
Manuscript ID	110986
Country	Spain

Category	Gastroenterology & Hepatology
Manuscript Type	Review
Article Title	Targetable pathways for drug repurposing in gastric cancer
Manuscript Source	Invited Manuscript
All Author List	Alba Valero-Almingol, Sheyla Montori, Nayra Felípez, Enrique Santamaría, Joaquín Fernandez-Irigoyen, Irina Luzko, Anabella A Cuestas, Carlos Pardo, Ricard Prat, Leticia Moreira and Eduardo Albéniz
Funding Agency and Grant Number	Funding Agency Grant Number Instituto de Salud Carlos III No. PI24/00784 Instituto de Salud Carlos III No. PI24/00737 Instituto de Salud Carlos III No. PI21/01181 Instituto de Salud Carlos III No. PI21/00333 Instituto de Salud Carlos III No. INT22/00112 Departamento de Universidad, Innovación y Transformación Digital Gobierno de Navarra No. 0011-1408-2024-000011 Departamento de Universidad, Innovación y Transformación Digital Gobierno de Navarra No. 0011-1408-2022-000010
Corresponding Author	Eduardo Albéniz, MD, PhD, Senior Researcher, Department of Gastroenterology, Hospital Universitario de Navarra, Navarrabiomed, Instituto de Investigación Sanitaria de Navarra, Universidad Pública de Navarra, Calle Irunlarrea, 3, Pamplona 31008, Navarre, Spain. eduardo.albeniz.arbizu@navarra.es
Key Words	Gastric cancer; Drug repurposing; Signaling pathways; Correa’s cascade; Cancer therapy
Core Tip	Gastric cancer patients have a dismal prognosis when it is detected in advanced stages, so the search for new treatments is imperative to improve survival rates. In this review, we explored the potential of repurposed drugs for targeting pathways related to the development and progression of gastric cancer, as their lower costs and faster development make them promising candidates in the search for new therapies to treat this disease.
Citation	Valero-Almingol A, Montori S, Felípez N, Santamaría E, Fernandez-Irigoyen J, Luzko I, Cuestas AA, Pardo C, Prat R, Moreira L, Albéniz E. Targetable pathways for drug repurposing in gastric cancer. World J Gastroenterol 2025; In press

Received	2025-06-20 02:24
Peer-Review Started	2025-06-20 02:24
To Make the First Decision
Return for Revision	2025-07-18 08:00
Revised	2025-07-31 10:19
Second Decision	2025-09-19 02:40
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-09-19 03:27
Articles in Press	2025-09-19 03:27
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright	© The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com