Publication Name	World Journal of Cardiology
Manuscript ID	111044
Country	Nepal

Category	Cardiac & Cardiovascular Systems
Manuscript Type	Meta-Analysis
Article Title	Fractional flow reserve guided percutaneous coronary intervention vs coronary artery bypass grafting for multivessel coronary artery disease: A meta-analysis
Manuscript Source	Unsolicited Manuscript
All Author List	Suhas Kataveni, Ezza Ellahi, Fabeha Zafar, Ihsan Noushad Karuppan Veettil, Amna Iqbal, Bhavya Dhir, Shivani Sabarish, Sai Erambalur, Meenakshi Reddy Yathindra, Moukthika Kvn, Shayan Nawaz, Satish Kumar Dudekula, Usman Ul Haq, Asraf Hussain and Muhammad Muneeb Khawar
Funding Agency and Grant Number
Corresponding Author	Asraf Hussain, MD, Department of Cardiology, Chitwan Medical College, Bharatpur-10, Chitwan, Nepal, Bharatpur 33915, Nepal. drasrafcardiology@gmail.com
Key Words	Percutaneous coronary intervention; Coronary artery bypass grafting; Fractional flow reserve; Multivessel coronary artery disease; Meta-analysis
Core Tip	This meta-analysis compares fractional flow reserve (FFR)-guided percutaneous coronary intervention (PCI) with coronary artery bypass grafting (CABG) for multivessel coronary artery disease. While both treatments show similar all-cause mortality and stroke rates, CABG significantly reduces major adverse cardiac events, myocardial infarction, and repeat revascularization. These findings highlight CABG’s superior efficacy in managing complex coronary disease, challenging the broader adoption of FFR-guided PCI. The results underscore the need for tailored treatment strategies and further trials to optimize outcomes in diverse patient populations.
Citation	Kataveni S, Ellahi E, Zafar F, Veettil INK, Iqbal A, Dhir B, Sabarish S, Erambalur S, Yathindra MR, Kvn M, Nawaz S, Dudekula SK, Ul Haq U, Hussain A, Khawar MM. Fractional flow reserve guided percutaneous coronary intervention vs coronary artery bypass grafting for multivessel coronary artery disease: A meta-analysis. World J Cardiol 2025; In press

Received	2025-06-23 13:34
Peer-Review Started	2025-06-23 13:34
To Make the First Decision
Return for Revision	2025-07-02 08:29
Revised	2025-07-05 19:54
Second Decision	2025-08-15 02:56
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-08-15 11:19
Articles in Press	2025-08-15 11:19
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ISSN	1949-8462 (online)
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