Publication Name	World Journal of Radiology
Manuscript ID	111076
Country	China

Category	Radiology, Nuclear Medicine & Medical Imaging
Manuscript Type	Review
Article Title	Stereotactic radiotherapy for brain metastases of non-small cell lung cancer: A comprehensive review
Manuscript Source	Invited Manuscript
All Author List	Aamir Khan, Hong-Fu Zhao, Hao Meng, Ning Wu and Lin-Lin Liu
Funding Agency and Grant Number
Corresponding Author	Ning Wu, MD, Professor, Department of Radiation Oncology, China-Japan Union Hospital of Jilin University, No.126 Xiantai Str, Changchun 130033, Jilin Province, China. wuning@jlu.edu.cn
Key Words	Lung carcinoma; Non-small cell lung cancer; Brain metastasis; Stereotactic radiotherapy; Blood–brain barrier; Tumor microenvironment
Core Tip	Stereotactic radiotherapy (SRT) offers a precise and effective treatment option for brain metastasis (BM) in patients with non-small cell lung cancer (NSCLC), providing better local tumor control, fewer side effects, and improved survival rates compared with the effects of traditional therapies. Integrating SRT with immunotherapy has displayed promise in enhancing intracranial progression-free survival, but further research is needed to optimize treatment protocols and refine multimodal therapy strategies for patients with NSCLC and BM.
Citation	Khan A, Zhao HF, Meng H, Wu N, Liu LL. Stereotactic radiotherapy for brain metastases of non-small cell lung cancer: A comprehensive review. World J Radiol 2025; In press

Received	2025-06-23 06:09
Peer-Review Started	2025-06-23 06:09
To Make the First Decision
Return for Revision	2025-07-03 11:01
Revised	2025-07-16 08:35
Second Decision	2025-08-08 02:43
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-08-08 07:51
Articles in Press	2025-08-08 07:51
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1949-8470 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
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