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Publication Name World Journal of Biological Chemistry
Manuscript ID 111104
Country India
Category Biochemistry & Molecular Biology
Manuscript Type Case Control Study
Article Title CD36 fatty-acid-transporter gene variants-CD36 G/A (rs1761667) and CD36 C/T (rs75326924) as biomarkers for risk-prediction in gestational diabetes mellitus
Manuscript Source Invited Manuscript
All Author List Amreen Shamsad, Tanu Gautam, Renu Singh and Monisha Banerjee
Funding Agency and Grant Number
Funding Agency Grant Number
Maulana Azad National Fellowship, University Grants Commission, New Delhi, Department of Biotechnology, New Delhi 82-27/2019 (SA III)
DBT-BUILDER-University of Lucknow Interdisciplinary Life Science Programme for Advance Research and Education (Level II) BT/INF/22/SP47623/2022
Department of Science and Technology -SERB Power Grant Scheme SPG/2021/00545
Corresponding Author Monisha Banerjee, PhD, Professor, Molecular and Human Genetics Laboratory, Department of Zoology, University of Lucknow, University Road, Lucknow 226007, Uttar Pradesh, India. monishabanerjee30@gmail.com
Key Words Association; Cluster of differentiation; Gene expression; Gene variants; Gestational diabetes mellitus; Polymerase chain reaction-restriction fragment length polymorphism
Core Tip Gestational diabetes mellitus (GDM) is a metabolic disorder causing hyperglycemia during pregnancy. GDM is associated with adverse feto-maternal outcomes, type-2-diabetes mellitus (T2DM), GDM-recurrence, future obesity. Insulin-resistance is a physiological trait associated with progressing pregnancy that provides an adequate nutritional supply for the mother and fetus. Disruptions in this mechanism might facilitate onset of GDM. CD36-transmembrane glycoprotein receptor, contributes to fatty-acid absorption. Genetic alterations in CD36 gene can modulate expression of genes along these pathways to mitigate the diabetic effect during pregnancy. The integration of genotyping-expression studies will be crucial for advancing investigation in GDM treatment.
Citation Shamsad A, Gautam T, Singh R, Banerjee M. CD36 fatty-acid-transporter gene variants-CD36 G/A (rs1761667) and CD36 C/T (rs75326924) as biomarkers for risk-prediction in gestational diabetes mellitus. World J Biol Chem 2025; In press
Received
2025-06-24 09:17
Peer-Review Started
2025-06-24 09:17
To Make the First Decision
Return for Revision
2025-07-30 07:54
Revised
2025-08-12 20:22
Second Decision
2025-11-06 02:42
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief
2025-11-07 03:18
Articles in Press
2025-11-07 03:18
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
ISSN 1949-8454 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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