Publication Name	World Journal of Gastrointestinal Endoscopy
Manuscript ID	111236
Country	India

Category	Medical Informatics
Manuscript Type	Systematic Reviews
Article Title	Advances in endoscopic dysplasia detection in inflammatory bowel disease
Manuscript Source	Invited Manuscript
All Author List	Partha Pal, Priyaranjan Kata, Zaheer Nabi, Mohan Ramchandani, Pramod Reddy Soma, Rajesh Gupta, Manu Tandan and Nageshwar Reddy Duvvur
Funding Agency and Grant Number
Corresponding Author	Partha Pal, FASGE, MD, MRCP, Department of Medical Gastroenterology, Asian Institute of Gastroenterology, 6-3-661 Red Rose Cafe Lane, Sangeet Nagar, Somajiguda, Hyderabad 500082, India. partha0123456789@gmail.com
Key Words	Colitis-associated neoplasia; Dye-based chromoendoscopy; Virtual chromoendoscopy; Narrow band imaging; White light endoscopy; High-definition endoscopy; Dysplasia; Biopsy
Core Tip	Dye-based chromoendoscopy (DCE), particularly with indigo carmine, provides high dysplasia detection rates and accurate lesion characterization in inflammatory bowel disease. While high-definition DCE may offer procedural advantages over high-definition white light endoscopy, detection superiority remains inconsistent. Virtual chromoendoscopy shows comparable dysplasia detection to DCE in several trials, with added efficiency and reduced procedure time. Targeted biopsies under image-enhanced endoscopy outperform or match random biopsies, with limited added value from random sampling except in select high-risk patients. Multimodal imaging and panoramic endoscopy enhance dysplasia yield. Despite strong evidence, real-world surveillance quality varies widely, highlighting the need for standardization.
Citation	Pal P, Kata P, Nabi Z, Ramchandani M, Soma PR, Gupta R, Tandan M, Duvvur NR. Advances in endoscopic dysplasia detection in inflammatory bowel disease. World J Gastrointest Endosc 2025; In press

Received	2025-06-26 07:17
Peer-Review Started	2025-06-26 07:20
To Make the First Decision
Return for Revision	2025-07-15 10:01
Revised	2025-07-24 03:34
Second Decision	2025-10-24 02:43
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-10-24 07:49
Articles in Press	2025-10-24 07:49
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ISSN	1948-5190 (online)
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