Publication Name	World Journal of Gastroenterology
Manuscript ID	111364
Country	China

Category	Gastroenterology & Hepatology
Manuscript Type	Retrospective Study
Article Title	Personalizing withdrawal time by insertion time to achieve target adenoma detection rate in colonoscopy
Manuscript Source	Unsolicited Manuscript
All Author List	Bing-Xin Xu, Cong-Zhou Xu, Hao-Yan Zhang, Xu-Jin Chen, Bing-Ni Wei and Cheng Yang
Funding Agency and Grant Number	Funding Agency Grant Number Young and Middle-Aged Talents Program of Wuxi Health Commission No. BJ2020011 Cohort Research Program of Wuxi Medical Center, Nanjing Medical University No. WMCC202314 Wuxi People’s Hospital 2024 “Wild Goose Array Talent” Reserve Discipline Leader No. 2024-YZ-HBDTR-YC-2024
Corresponding Author	Cheng Yang, MD, Department of Gastroenterology, The Affiliated Wuxi People’s Hospital of Nanjing Medical University, Wuxi People’s Hospital, Wuxi Medical Center, Nanjing Medical University, No. 299 Qingyang Road, Liangxi District, Wuxi 214023, Jiangsu Province, China. yangchengds@163.com
Key Words	Colonoscopy; Withdrawal time; Insertion time; Adenoma detection rate; Machine learning
Core Tip	This study identifies four key predictors of ≥ 25% adenoma detection rate (ADR), age, sex, endoscopist experience, and withdrawal time and develops a validated hybrid support vector machine extreme gradient boosting model to predict ADR. Using data from 6529 colonoscopies, the model demonstrated stable performance and was implemented in a Shiny app for real-time clinical use. This innovative tool offers personalized guidance to optimize colonoscopy quality and improve clinical outcomes, representing a significant advancement in endoscopic decision support.
Citation	Xu BX, Xu CZ, Zhang HY, Chen XJ, Wei BN, Yang C. Personalizing withdrawal time by insertion time to achieve target adenoma detection rate in colonoscopy. World J Gastroenterol 2025; In press

Received	2025-07-01 07:10
Peer-Review Started	2025-07-01 07:11
To Make the First Decision
Return for Revision	2025-07-21 09:19
Revised	2025-08-02 16:56
Second Decision	2025-09-05 02:39
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-09-05 06:20
Articles in Press	2025-09-05 06:20
Publication Fee Transferred	2025-08-04 12:58
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1007-9327 (print) and 2219-2840 (online)
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