Publication Name	World Journal of Methodology
Manuscript ID	111566
Country	Nepal

Category	Cardiac & Cardiovascular Systems
Manuscript Type	Meta-Analysis
Article Title	Sirolimus vs paclitaxel-coated balloons in in-stent coronary restenosis: A meta-analysis
Manuscript Source	Unsolicited Manuscript
All Author List	Debvarsha Mandal, Thomas Viji Pulickal, Dhritika Ahlawat, Wasiullah Haqbeen, Izma Kashif, Haroon Alamy, Pramoda Prattipati, Padmavathi Jaladi, Paula Kabiaru, Anjali Avula, Sandeep Kshetri, Irum Raza, Samir Shamieh and Rejina Chhetri
Funding Agency and Grant Number
Corresponding Author	Rejina Chhetri, MD, Department of Cardiology, Nepalgunj Medical College, Nepalgunj Medical College Chisapani Banke Baijanath 1 Chisapani, Kohal 21900, Nepal. rejinachhetri01@gmail.com
Key Words	Sirolimus coated balloon; Paclitaxel coated balloon; In-stent restenosis; Coronary interventions; Cardiovascular outcomes
Core Tip	This meta-analysis systematically compares sirolimus-coated balloons (SCBs) and paclitaxel-coated balloons (PCBs) for treating coronary in-stent restenosis (ISR). Synthesizing data from randomized controlled trials and observational studies, the findings demonstrate no significant differences between SCBs and PCBs in efficacy or safety outcomes, including target lesion revascularization and major adverse cardiovascular events. These results support flexible clinical use of either DCB type for ISR, while highlighting the need for further research into long-term outcomes and high-risk patient subgroups.
Citation	Mandal D, Pulickal TV, Ahlawat D, Haqbeen W, Kashif I, Alamy H, Prattipati P, Jaladi P, Kabiaru P, Avula A, Kshetri S, Raza I, Shamieh S, Chhetri R. Sirolimus vs paclitaxel-coated balloons in in-stent coronary restenosis: A meta-analysis. World J Methodol 2025; In press

Received	2025-07-03 04:13
Peer-Review Started	2025-07-03 04:13
To Make the First Decision
Return for Revision	2025-08-05 08:46
Revised	2025-08-06 18:56
Second Decision	2025-08-28 02:40
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-08-28 07:30
Articles in Press	2025-08-28 07:30
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	2222-0682 (online)
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