Publication Name	World Journal of Psychiatry
Manuscript ID	112055
Country	China

Category	Pharmacology & Pharmacy
Manuscript Type	Basic Study
Article Title	Investigating the pharmaceutical substances and action mechanisms of Changmaxifeng granules against tic disorders
Manuscript Source	Unsolicited Manuscript
All Author List	Li-Dong Xie, Jian-Ping Wu, Shu-Sen Liu, Zheng Zong, Yang Hu, Na Ling, Bing Han, Wen-Lan Li and Hong-Yan Yao
Funding Agency and Grant Number	Funding Agency Grant Number Key Research and Development Plan Project of Heilongjiang Province 2022ZX02C08 Heilongjiang Science and Technology Talent Spring Swallow Support Program Project CYCX24009 2025 Graduate Innovation Research Funding Project of Harbin University of Commerce YJSCX2025-833HSD
Corresponding Author	Wen-Lan Li, Professor, School of Pharmacy, Harbin University of Commerce, No. 138 Tongda Street, Daoli District, Harbin 150076, Heilongjiang Province, China. lwldzd@163.com
Key Words	Changmaxifeng granule; Against tic disorders; Chemical components; Network pharmacology; Molecular docking
Core Tip	Clinical studies have shown that Changmaxifeng granules (CG) can treat tic disorders. However, the pharmaceutical substances and mechanism of action of CG remain unclear. In this study, we combined serum pharmacochemistry with network pharmacology to identify the chemical constituents of CG that enter the bloodstream and to predict their potential molecular targets, thereby laying the groundwork for elucidating the underlying mechanisms of action.
Citation	Xie LD, Wu JP, Liu SS, Zong Z, Hu Y, Ling N, Han B, Li WL, Yao HY. Investigating the pharmaceutical substances and action mechanisms of Changmaxifeng granules against tic disorders. World J Psychiatry 2025; In press

Received	2025-07-17 03:11
Peer-Review Started	2025-07-17 03:12
To Make the First Decision
Return for Revision	2025-07-30 07:25
Revised	2025-08-11 17:37
Second Decision	2025-09-04 02:48
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-09-04 07:39
Articles in Press	2025-09-04 07:39
Publication Fee Transferred	2025-08-15 01:31
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	2220-3206 (online)
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