Publication Name	World Journal of Clinical Pediatrics
Manuscript ID	112145
Country	Norway

Category	Pediatrics
Manuscript Type	Minireviews
Article Title	Modulatory role of vitamin D in atopic dermatitis and allergic rhinitis
Manuscript Source	Invited Manuscript
All Author List	Chandra Sekhar Devulapalli
Funding Agency and Grant Number
Corresponding Author	Chandra Sekhar Devulapalli, Consultant, MD, PhD, Senior Researcher, Senior Scientist, Pediatric Outpatient Clinic, Department of Medicine, Helgeland Hospital, Prestmarkveien 1, Alstahaug (Sandnessjøen) NO-8800, Nordland, Norway. chandev@gmail.com
Key Words	Vitamin D; Atopic dermatitis; Allergic rhinitis; Pediatric allergy; Immune modulation; Epithelial barrier function; Vitamin D receptor; Allergic sensitization; Early-life immunity; Genetic polymorphism
Core Tip	Vitamin D has emerged as a key modulator of immune responses and epithelial barrier integrity relevant to pediatric atopic dermatitis and allergic rhinitis (AR). Recent evidence highlights phenotype-specific effects, particularly in children with allergic sensitization, and suggests stronger associations with seasonal AR. Advances in vitamin D receptor biology and genomics support a personalized approach to supplementation. Early-life vitamin D exposure may influence immune development and disease trajectory, underscoring the potential for preventive and therapeutic applications in pediatric allergy care.
Citation	Devulapalli CS. Modulatory role of vitamin D in atopic dermatitis and allergic rhinitis. World J Clin Pediatr 2025; In press

Received	2025-07-21 01:40
Peer-Review Started	2025-07-21 01:40
To Make the First Decision
Return for Revision	2025-08-06 10:39
Revised	2025-08-07 16:52
Second Decision	2025-09-15 02:42
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-09-17 10:37
Articles in Press	2025-09-17 10:37
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	2219-2808 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright	The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com