Publication Name	World Journal of Gastrointestinal Oncology
Manuscript ID	112248
Country	China

Category	Gastroenterology & Hepatology
Manuscript Type	Minireviews
Article Title	Reassessing the role of lymph node dissection in pancreatic cancer surgery: Balancing oncologic control and immune function preservation
Manuscript Source	Invited Manuscript
All Author List	Yi-Han Xu and Yan Jiao
Funding Agency and Grant Number
Corresponding Author	Yan Jiao, Department of Hepatobiliary and Pancreatic Surgery, General Surgery Center, The First Hospital of Jilin University, Xinmin Street, Changchun 130021, Jilin Province, China. jiaoyan@jlu.edu.cn
Key Words	Pancreatic cancer; Lymphadenectomy; Extended lymph node dissection; Immune response; Surgical oncology; Tumor microenvironment
Core Tip	The extent of lymph node dissection in pancreatic cancer surgery remains contentious. While extended lymphadenectomy does not improve survival outcomes, it increases morbidity and may impair immune function. This minireview calls for a more individualized approach to lymphadenectomy, considering both oncologic efficacy and immune preservation, in line with the evolving landscape of immunotherapy.
Citation	Xu YH, Jiao Y. Reassessing the role of lymph node dissection in pancreatic cancer surgery: Balancing oncologic control and immune function preservation. World J Gastrointest Oncol 2025; In press

Received	2025-07-22 04:16
Peer-Review Started	2025-07-22 04:16
To Make the First Decision
Return for Revision	2025-08-05 08:18
Revised	2025-08-07 05:18
Second Decision	2025-09-28 02:42
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-09-28 10:34
Articles in Press	2025-09-28 10:34
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1948-5204 (online)
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