Publication Name	World Journal of Psychiatry
Manuscript ID	112431
Country	China

Category	Psychiatry
Manuscript Type	Randomized Controlled Trial
Article Title	Computerized cognitive behavioral therapy with sertraline in schizophrenia with depressive episodes: A 12-week randomized controlled trial
Manuscript Source	Unsolicited Manuscript
All Author List	Ren-Chun Huang, Nicha Wareesawetsuwan, Nan Lin and Xiao-Dan Li
Funding Agency and Grant Number	Funding Agency Grant Number Fuzhou Science and Technology Plan Project 2023-S-028
Corresponding Author	Xiao-Dan Li, MD, PhD, Department of Psychiatry, The Second General Hospital of Fuzhou Neuropsychiatric Prevention and Treatment Hospital, No. 451, South Second Ring Road, Fuzhou 350004, China. 810538265@qq.com
Key Words	Schizophrenia with depressive episode; Computerized cognitive behavioral therapy; Sertraline; Cognitive function; Quality of life; Randomized controlled trial
Core Tip	This randomized controlled trial demonstrates that combining computerized cognitive behavioral therapy (CCBT) with sertraline is more effective than sertraline alone in improving depressive symptoms, cognitive function, and quality of life in patients with schizophrenia and depressive episodes. Notably, CCBT significantly enhanced processing speed and social cognition. These findings support CCBT as a scalable, accessible, and effective adjunct to pharmacotherapy in this challenging population.
Citation	Huang RC, Wareesawetsuwan N, Lin N, Li XD. Computerized cognitive behavioral therapy with sertraline in schizophrenia with depressive episodes: A 12-week randomized controlled trial. World J Psychiatry 2025; In press

Received	2025-07-28 05:05
Peer-Review Started	2025-07-28 05:05
To Make the First Decision
Return for Revision	2025-07-31 07:29
Revised	2025-08-09 16:37
Second Decision	2025-09-04 02:48
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-09-04 09:43
Articles in Press	2025-09-04 09:43
Publication Fee Transferred	2025-08-12 05:43
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	2220-3206 (online)
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