Publication Name	World Journal of Gastrointestinal Pharmacology and Therapeutics
Manuscript ID	112803
Country	Croatia

Category	Gastroenterology & Hepatology
Manuscript Type	Retrospective Cohort Study
Article Title	Impact of sedation on adenoma and polyp detection rates and cecal intubation in elderly patients undergoing screening colonoscopy
Manuscript Source	Invited Manuscript
All Author List	Vedran Tomasic, Petra Ćaćić, Irma Siranovic Pongrac, Stipe Pelajić, Neven Barsic, Andrea Arefijev, Ivan Lerotic, Ante Blazevic and Alen Bišćanin
Funding Agency and Grant Number
Corresponding Author	Vedran Tomasic, Assistant Professor, Consultant, MD, PhD, Division of Endoscopy and Day Hospital, Department of Internal Medicine, University Hospital Centre “Sestre Milosrdnice”, Vinogradska cesta 150, Zagreb 10000, Croatia. tomasicvedran@gmail.com
Key Words	Screening colonoscopy; Elderly; Sedation; Propofol sedation; Adenoma detection rate; Polyp detection rate; Cecal intubation rate; Colorectal carcinoma; Obesity
Core Tip	Increasing life expectancy and population aging have increased the incidence of colorectal adenomas and cancers, especially among elderly individuals with obesity. Individual health assessments are crucial, as strict age-based decision-making alone is insufficient. Physicians need to prioritize both patient comfort and procedural safety when considering sedation. Although sedation may not boost overall detection and completion rates, it may be beneficial for obese, male, and late-elderly patients. Effective bowel preparation is the key factor influencing colonoscopy completion in the elderly. Therefore, providing additional guidance and support on bowel preparation is essential for obese elderly men to improve colonoscopy outcomes.
Citation	Tomasic V, Ćaćić P, Siranovic Pongrac I, Pelajić S, Barsic N, Arefijev A, Lerotic I, Blazevic A, Bišćanin A. Impact of sedation on adenoma and polyp detection rates and cecal intubation in elderly patients undergoing screening colonoscopy. World J Gastrointest Pharmacol Ther 2026; In press

Received	2025-08-06 15:03
Peer-Review Started	2025-08-06 15:04
First Decision by Editorial Office Director	2025-10-10 09:10
Return for Revision	2025-10-10 09:10
Revised	2025-10-23 10:56
Publication Fee Transferred
Second Decision by Editor	2026-01-04 02:47
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-01-04 10:12
Articles in Press	2026-01-04 10:12
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	2150-5349 (online)
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