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Publication Name World Journal of Gastrointestinal Surgery
Manuscript ID 112906
Country United Kingdom
Category Surgery
Manuscript Type Retrospective Study
Article Title Biliary complications following donation after brainstem death liver transplantation
Manuscript Source Invited Manuscript
All Author List Rawan Al-Rubaye, Mohamed Elshaer, Karim R Moawad and Rohit Gaurav
Funding Agency and Grant Number
Corresponding Author Mohamed Elshaer, FRCS (Gen Surg), MD, Department of Hepato-Pancreato-Biliary and Transplantation Surgery, Cambridge University Hospitals, Addenbrooke’s Hospital, Hills Road, Cambridge cb2 0qq, Cambridgeshire, United Kingdom. mohamed.elshaer@nhs.net
Key Words Biliary stricture; Anastomotic biliary stricture; Biliary complications; Donation after brainstem death; Liver transplant
Core Tip This retrospective study of 366 liver transplant after brainstem death, demonstrates that anastomotic biliary stricture remains a significant complication, occurring in 10.7% of patients. Roux-en-Y hepaticojejunostomy (RYHJ) was associated with significantly lower rates of bile leaks and anastomotic strictures compared to duct-to-duct anastomosis. However, patients undergoing primary RYHJ had higher reoperation and retransplantation rates, primarily due to selection bias, as RYHJ was preferentially performed in patients with complex recipient pathology. Early detection and appropriate management with a stepwise approach—from endoscopic intervention to surgical revision—are crucial for optimising post-transplant outcomes.
Citation

Al-Rubaye R, Elshaer M, Moawad KR, Gaurav R. Biliary complications following donation after brainstem death liver transplantation. World J Gastrointest Surg 2026; 18(1): 112906

Received
2025-08-27 10:56
Peer-Review Started
2025-08-27 10:56
First Decision by Editorial Office Director
2025-09-25 03:12
Return for Revision
2025-09-25 03:12
Revised
2025-10-20 19:14
Publication Fee Transferred
Second Decision by Editor
2025-11-11 02:42
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2025-11-11 08:29
Articles in Press
2025-11-11 08:29
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-01-12 02:12
ISSN 1948-9366 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
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