BPG is committed to discovery and dissemination of knowledge
Articles in Press
12/5/2025 5:19:55 AM | Browse: 171 | Download: 1
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Prospective Study |
| Article Title |
Interleukin-6/interleukin-10 ratio and immune dysregulation after radiofrequency ablation
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Lei Pang, Di Tang, Wan-Lin Zhou, Xin Bai, Hui-Jia Zhao, Li-Qiang Wang, Wen Cheng and Bo-Lin Wu |
| Funding Agency and Grant Number |
|
| Corresponding Author |
Bo-Lin Wu, Professor, Department of Ultrasound, Harbin Medical University Cancer Hospital, No. 150 Haping Road, Nangang District, Harbin 150000, Heilongjiang Province, China. wubolin@hrbmu.edu.cn |
| Key Words |
Interleukin-6/interleukin-10 ratio; Immune dysregulation; Radiofrequency ablation; Hepatic malignancies; Inflammatory biomarkers |
| Core Tip |
This study confirms that the post-procedural interleukin-6/interleukin-10 ratio serves as an independent prognostic biomarker for immune dysregulation in patients with malignant liver tumors following radiofrequency ablation. A persistently elevated ratio was significantly associated with adverse clinical outcomes, reflecting an immune imbalance dominated by a proinflammatory state. This highlights the clinical value of dynamic cytokine monitoring, with early postoperative measurements providing a practical tool for risk stratification. This metric can serve as a foundational parameter for developing comprehensive predictive models in the future, and its integration with clinical characteristics will advance the development of personalized management strategies after radiofrequency ablation. |
| Citation |
Pang L, Tang D, Zhou WL, Bai X, Zhao HJ, Wang LQ, Cheng W, Wu BL. Interleukin-6/interleukin-10 ratio and immune dysregulation after radiofrequency ablation. World J Hepatol 2026; 18(1): 113429 |
 |
Received |
|
2025-08-26 01:16 |
|
Peer-Review Started |
|
2025-08-26 01:16 |
|
First Decision by Editorial Office Director |
|
2025-09-18 09:30 |
|
Return for Revision |
|
2025-09-18 09:30 |
|
Revised |
|
2025-09-29 02:34 |
|
Publication Fee Transferred |
|
2025-09-30 12:23 |
|
Second Decision by Editor |
|
2025-12-05 02:34 |
 |
Second Decision by Editor-in-Chief |
|
|
|
Final Decision by Editorial Office Director |
|
2025-12-05 05:19 |
|
Articles in Press |
|
2025-12-05 05:19 |
|
Edit the Manuscript by Language Editor |
|
|
|
Typeset the Manuscript |
|
2026-01-13 00:32 |
| ISSN |
1948-5182 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
|
| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
© 1993-2026 Baishideng Publishing Group Inc. All rights reserved. 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
California Corporate Number: 3537345
