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Publication Name World Journal of Gastroenterology
Manuscript ID 113541
Country Spain
Category Gastroenterology & Hepatology
Manuscript Type Observational Study
Article Title Lack of follow-up in Helicobacter pylori eradication treatment: Results from the European registry on Helicobacter pylori management
Manuscript Source Unsolicited Manuscript
All Author List Elisa Cantú-Germano, Leticia Moreira, Ángeles Pérez-Aisa, Samuel J Martínez-Domínguez, Irina Voynovan, Luis Bujanda, Laimas Jonaitis, Bojan Tepes, Ana Garre, Alfredo J Lucendo, Frode Lerang, Thomas Butler, Umud Mahmudov, Jose M Huguet, Javier Tejedor-Tejada, Pavel Bogomolov, Ian LP Beales, Perminder S Phull, Manuel Pabon-Carrasco, Manuel Castro-Fernández, Sergey Alekseenko, Matteo Pavoni, Oleg Zaytsev, Renate Bumane, Maja Denkovski, Manuel D Cajal, Ilchishina Tatiana, Miguel Areia, Alma Keco-Huerga, Gülüstan Babayeva, Fernando Bermejo, Halis Simsek, György M Buzás, Giuseppe Losurdo, Dmitry S Bordin, Juozas Kupcinskas, Sinead M Smith, Antonio Gasbarrini, Marcis Leja, Ricardo Marcos-Pinto, Cem Simsek, Veronika Papp, Blas JG Rodríguez, Pilar P Mejide, Ramón P Villarroya, Mónica S Alonso, Anna Cano-Català, Francis Megraud, Colm O’Morain, Pablo Parra, Olga P Nyssen and Javier P Gisbert
Funding Agency and Grant Number
Funding Agency Grant Number
European Union program HORIZON No. 101095359
European Union program EU4Health No. 101101252
Corresponding Author Leticia Moreira, Department of Gastroenterology, Hospital Clínic de Barcelona, Carrer de Villarroel, 170, L’Eixample, Barcelona 08036, Catalonia, Spain. lmoreira@clinic.cat
Key Words Helicobacter pylori; Eradication treatment; Eradication failure; Retreatment; European registry on Helicobacter pylori management
Core Tip This multicenter European study found that 14% of patients in whom Helicobacter pylori (H. pylori) eradication treatment failed did not receive retreatment, often due to patient-driven decisions and medical considerations such as advanced age, previous noncompliance, and treatment intolerance. Identifying these barriers emphasizes the need for shared decision-making and enhanced patient education to improve management outcomes. These findings provide crucial insights into real-world challenges in H. pylori infection management and offer guidance for optimizing treatment strategies in line with the recommendations of Maastricht VI/Florence.
Citation Cantú-Germano E, Moreira L, Pérez-Aisa Á, Martínez-Domínguez SJ, Voynovan I, Bujanda L, Jonaitis L, Tepes B, Garre A, Lucendo AJ, Lerang F, Butler T, Mahmudov U, Huguet JM, Tejedor-Tejada J, Bogomolov P, Beales ILP, Phull PS, Pabon-Carrasco M, Castro-Fernández M, Alekseenko S, Pavoni M, Zaytsev O, Bumane R, Denkovski M, Cajal MD, Tatiana I, Areia M, Keco-Huerga A, Babayeva G, Bermejo F, Simsek H, Buzás GM, Losurdo G, Bordin DS, Kupcinskas J, Smith SM, Gasbarrini A, Leja M, Marcos-Pinto R, Simsek C, Papp V, Rodríguez BJG, Mejide PP, Villarroya RP, Alonso MS, Cano-Català A, Megraud F, O’Morain C, Parra P, Nyssen OP, Gisbert JP. Lack of follow-up in Helicobacter pylori eradication treatment: Results from the European registry on Helicobacter pylori management. World J Gastroenterol 2025; In press
Received
2025-08-29 08:47
Peer-Review Started
2025-08-29 08:48
First Decision by Editorial Office Director
2025-09-17 09:18
Return for Revision
2025-09-17 09:18
Revised
2025-09-30 15:48
Publication Fee Transferred
2025-10-05 20:08
Second Decision by Editor
2025-12-30 02:36
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2025-12-30 08:12
Articles in Press
2025-12-30 08:12
Edit the Manuscript by Language Editor
Typeset the Manuscript
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
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