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Articles in Press
12/4/2025 6:53:11 AM | Browse: 143 | Download: 2
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Randomized Controlled Trial |
| Article Title |
Lactated Ringer’s solution in combination with indomethacin for prevention of post-endoscopic retrograde cholangiopancreatography pancreatitis: A prospective, randomized trial
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Khellaf Amalou, Nadjib Benboudiaf, Mohamed Tahar Medkour, Farid Belghanem, Hana Chetroub, Ryma Rekab, Ahlem Belloula, Fateh Bouaouina and Khadidja Saidani |
| Funding Agency and Grant Number |
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| Corresponding Author |
Khellaf Amalou, Assistant Professor, PhD, Department of Gastroenterology, Mohamed Seghir Nekkache, Kouba 246, Algiers 16000, Algeria. amalou_kh@yahoo.fr |
| Key Words |
Lactated Ringer’s solution; Indomethacin; Post-endoscopic retrograde cholangiopancreatography pancreatitis; Efficacy; Outcomes |
| Core Tip |
Endoscopic retrograde cholangiopancreatography is an important technique for the diagnosis and treatment of pancreaticobiliary disorders. Post-endoscopic retrograde cholangiopancreatography pancreatitis (PEP) is the most prevalent complication relating to endoscopic retrograde cholangiopancreatography. Rectal nonsteroidal anti-inflammatory drugs and prophylactic pancreatic stent insertion remain advised for its prevention. The administration of lactated Ringer’s solution (LR) plays an important part in preventing pancreatic necrosis and organ failure by sustaining steady pancreatic microcirculation. This randomized, double-blind, controlled study showed that the infusion of LR combined with rectal indomethacin (IND) may decrease the occurrence of PEP and post-procedure readmission in high-risk patients, compared to LR or IND administered separately. |
| Citation |
Amalou K, Benboudiaf N, Medkour MT, Belghanem F, Chetroub H, Rekab R, Belloula A, Bouaouina F, Saidani K. Lactated Ringer’s solution in combination with indomethacin for prevention of post-endoscopic retrograde cholangiopancreatography pancreatitis: A prospective, randomized trial. World J Gastrointest Endosc 2026; 18(1): 113788 |
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Received |
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2025-09-04 06:09 |
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Peer-Review Started |
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2025-09-04 06:09 |
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First Decision by Editorial Office Director |
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2025-10-17 07:44 |
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Return for Revision |
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2025-10-17 07:44 |
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Revised |
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2025-10-29 22:28 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2025-12-04 02:35 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2025-12-04 06:53 |
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Articles in Press |
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2025-12-04 06:53 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2026-01-05 01:33 |
| ISSN |
1948-5190 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
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