Publication Name	World Journal of Gastrointestinal Pharmacology and Therapeutics
Manuscript ID	113874
Country	Ireland

Category	Gastroenterology & Hepatology
Manuscript Type	Retrospective Cohort Study
Article Title	Right biopsy protocol for microscopic colitis: Reduced workload and carbon footprint while maintaining diagnostic accuracy
Manuscript Source	Unsolicited Manuscript
All Author List	Edric Leung, Yasir Alshareefy, Conor Costigan, Sandeep Sihag, Sarah Delaney, Sarah O’Donnell, Niall Breslin, Anthony O’Connor, Barbara Ryan, Abdul Zaheer, Ion Cretu, Fintan O’Hara and Deirdre McNamara
Funding Agency and Grant Number
Corresponding Author	Edric Leung, Department of Gastroenterology, Tallaght University Hospital, Tallaght, Dublin D24 NR0A, Ireland. edric.leung@tuh.ie
Key Words	Microscopic colitis; Colon biopsy; Biopsy protocol; Diagnostic yield; Green endoscopy; Chronic diarrhoea
Core Tip	Current guidelines recommend biopsies from both right and left colon for diagnosing microscopic colitis, yet the optimal strategy is uncertain. In this retrospective study of 228 index colonoscopies from patients with microscopic colitis, right colon biopsies were diagnostic in all cases, while left colon biopsies had a significantly lower yield and provided no additional diagnostic value. These findings suggest that a simplified protocol of two right colon biopsies in a single container could preserve diagnostic accuracy while reducing workload, cost, and carbon footprint, consistent with green endoscopy principles.
Citation	Leung E, Alshareefy Y, Costigan C, Sihag S, Delaney S, O’Donnell S, Breslin N, O’Connor A, Ryan B, Zaheer A, Cretu I, O’Hara F, McNamara D. Right biopsy protocol for microscopic colitis: Reduced workload and carbon footprint while maintaining diagnostic accuracy. World J Gastrointest Pharmacol Ther 2026; In press

Received	2025-09-09 10:07
Peer-Review Started	2025-09-09 10:07
First Decision by Editorial Office Director	2025-10-30 09:23
Return for Revision	2025-10-30 13:26
Revised	2025-11-13 02:58
Publication Fee Transferred	2025-12-11 19:06
Second Decision by Editor	2026-01-27 02:40
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-01-27 03:34
Articles in Press	2026-01-27 03:34
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	2150-5349 (online)
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