| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Clinical Trials Study |
| Article Title |
Efficacy and safety of a novel sodium picosulfate oral tablet in a randomized controlled trial for bowel preparation
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Su Bum Park, Sang Bum Kang, Geom Seog Seo, Chang Soo Eun, Chang Hwan Choi, Dong-Hoon Yang, Jae Jun Park, Chang Mo Moon, Sung Hoon Jung, Hyung Park, Mi Hee Park, Ho Kyun Yoo, Jiwon Kim, Jung A Heo and Dong Il Park |
| Funding Agency and Grant Number |
|
| Corresponding Author |
Dong Il Park, MD, PhD, Professor, Department of Internal Medicine and Gastrointestinal Cancer Center, Samsung Kangbuk Hospital, Sungkyunkwan University School of Medicine, 29 Saemunan-Ro, Jongno-Gu, Seoul 03181, South Korea. diksmc.park@samsung.com |
| Key Words |
DWJ1609; Sodium picosulfate; Oral sulfate tablets; Bowel preparation; Colon cleansing |
| Core Tip |
This multicenter randomized trial evaluated DWJ1609, a newly formulated oral sulfate tablet that incorporates sodium picosulfate with reduced sulfate content. DWJ1609 demonstrated non-inferior bowel cleansing efficacy compared with conventional oral sulfate tablets, while requiring fewer tablets and showing improved tolerability. These findings highlight DWJ1609 as a clinically meaningful alternative that may enhance patient acceptance and optimize colonoscopy preparation. This study provides evidence supporting its effectiveness and safety in routine practice, while noting the need for future research in older adults and patients with comorbidities. |
| Citation |
Park SB, Kang SB, Seo GS, Eun CS, Choi CH, Yang DH, Park JJ, Moon CM, Jung SH, Park H, Park MH, Yoo HK, Kim J, Heo JA, Park DI. Efficacy and safety of a novel sodium picosulfate oral tablet in a randomized controlled trial for bowel preparation. World J Gastroenterol 2025; In press |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
|
| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
