Publication Name	World Journal of Gastrointestinal Oncology
Manuscript ID	114163
Country	China

Category	Oncology
Manuscript Type	Letter to the Editor
Article Title	Role of microRNA-136 in Helicobacter pylori-induced early-stage gastric cancer: Mechanistic insights and future directions
Manuscript Source	Invited Manuscript
All Author List	Yi-Xiao Chen, Ying-Hua Zhang and Sai-Jun Mo
Funding Agency and Grant Number	Funding Agency Grant Number Foundation of Henan Educational Committee 26A310017 Natural Science Foundation for Young Teachers’ Basic Research of Zhengzhou University JC202035025 College Student Innovation and Entrepreneurship Competitions 202510459174, 2025cxcy639
Corresponding Author	Sai-Jun Mo, Associate Professor, PhD, Department of Pathophysiology, School of Basic Medical Sciences, Zhengzhou University, No. 100 Science Avenue, Zhongyuan District, Zhengzhou 450001, Henan Province, China. sjmo@zzu.edu.cn
Key Words	Helicobacter pylori; MicroRNA-136; Programmed cell death protein 11; Nuclear factor kappa B; Gastric carcinogenesis
Core Tip	This study identified microRNA-136 as a potential diagnostic biomarker and therapeutic target for early-stage gastric cancer, demonstrating its role in tumor growth and metastasis through in vitro and in vivo models. Targeting the nuclear factor kappa B/microRNA-136/programmed cell death protein 11 axis may offer new strategies for intervention.
Citation	Chen YX, Zhang YH, Mo SJ. Role of microRNA-136 in Helicobacter pylori-induced early-stage gastric cancer: Mechanistic insights and future directions. World J Gastrointest Oncol 2025; In press

Received	2025-09-15 03:03
Peer-Review Started	2025-09-15 03:03
First Decision by Editorial Office Director	2025-09-30 07:58
Return for Revision	2025-09-30 07:58
Revised	2025-10-08 05:00
Publication Fee Transferred
Second Decision by Editor	2025-12-03 02:40
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2025-12-03 08:54
Articles in Press	2025-12-03 08:54
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1948-5204 (online)
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