Publication Name	World Journal of Cardiology
Manuscript ID	114265
Country	Russia

Category	Cardiac & Cardiovascular Systems
Manuscript Type	Meta-Analysis
Article Title	Oral anticoagulant therapy and outcomes in new-onset atrial fibrillation during acute myocardial infarction: A systematic review and meta-analysis
Manuscript Source	Invited Manuscript
All Author List	Kristina G Pereverzeva, Ayoub Glenza and Sergey S Yakushin
Funding Agency and Grant Number
Corresponding Author	Kristina G Pereverzeva, Associate Professor, MD, PhD, Department of Hospital Therapy, Federal State Budgetary Educational Institution of Higher Education, Ryazan State Medical University, 96 Stroykova Street, Ryazan 390026, Ryazanskaya Oblast, Russia. pereverzevakg@gmail.com
Key Words	New-onset atrial fibrillation; Acute myocardial infarction; Oral anticoagulants; Mortality; Stroke; Bleeding
Core Tip	New-onset atrial fibrillation during acute myocardial infarction is a frequent and high-risk complication, yet evidence for optimal long-term management is limited due to exclusion from randomized trials. This meta-analysis of 7158 patients demonstrated that oral anticoagulant therapy reduced all-cause mortality by 25% without increasing major bleeding risk. The findings support guideline recommendations to consider anticoagulation in this population, particularly in patients with higher thromboembolic risk. Importantly, the results highlighted the urgent need for randomized trials focusing on direct oral anticoagulants and transient atrial fibrillation in the context of acute myocardial infarction.
Citation	Pereverzeva KG, Glenza A, Yakushin SS. Oral anticoagulant therapy and outcomes in new-onset atrial fibrillation during acute myocardial infarction: A systematic review and meta-analysis. World J Cardiol 2025; In press

Received	2025-09-15 02:26
Peer-Review Started	2025-09-15 02:27
First Decision by Editorial Office Director	2025-09-18 09:26
Return for Revision	2025-09-18 09:26
Revised	2025-10-02 09:10
Publication Fee Transferred
Second Decision by Editor	2025-12-10 02:47
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2025-12-10 09:57
Articles in Press	2025-12-10 09:57
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1949-8462 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright	© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com