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Articles in Press
12/5/2025 8:04:49 AM | Browse: 77 | Download: 0
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Letter to the Editor |
| Article Title |
Inflammation, immunity, and gastric ulcer — clinical insights from routine haematology
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Hui Wang and Shi-San Bao |
| Funding Agency and Grant Number |
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| Corresponding Author |
Shi-San Bao, Additional Professor, Pathology, Pathology, University of Sydney, Sydney, New South Wales 2006, Australia, Faculty of Medicine and Health
The University of Sydney, Sydney 2006, New South Wales, Australia. profbao@hotmail.com |
| Key Words |
Inflammation; Immunity; Gastric ulcer; Systemic immune-inflammation index; Routine haematology |
| Core Tip |
Gastric ulcer remains a significant health concern with serious complications. This study shows that six complete blood count (CBC)-derived inflammatory indices—neutrophil-to-lymphocyte ratio, monocyte-to-lymphocyte ratio, platelet-to-lymphocyte ratio, systemic immune-inflammation index, systemic inflammatory response index (SIRI), and aggregate index of systemic inflammation—are associated with gastric ulcer, with SIRI demonstrating the strongest predictive value (area under the curve = 0.868). As CBC is widely available, inexpensive, and reproducible, these indices may serve as practical, non-invasive tools for identifying at-risk patients and supplementing traditional risk factors. The findings emphasise the role of systemic inflammation in gastric ulcer pathogenesis and warrant prospective validation. |
| Citation |
Wang H, Bao SS. Inflammation, immunity, and gastric ulcer — clinical insights from routine haematology. World J Gastroenterol 2026; 32(3): 114347 |
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Received |
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2025-09-16 11:34 |
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Peer-Review Started |
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2025-09-16 11:34 |
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First Decision by Editorial Office Director |
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2025-11-18 10:47 |
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Return for Revision |
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2025-11-18 10:47 |
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Revised |
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2025-11-24 08:20 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2025-12-05 02:34 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2025-12-05 08:04 |
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Articles in Press |
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2025-12-05 08:04 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2025-12-30 09:35 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
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