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Articles in Press
12/3/2025 9:07:13 AM | Browse: 20 | Download: 0
| Category |
Pediatrics |
| Manuscript Type |
Randomized Controlled Trial |
| Article Title |
Efficacy of vitamin D supplementation for children with acute bronchiolitis: A randomized controlled trial
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Elsayed Abdelkreem, Yostena Safwat Labeeb and Mostafa Ashry Mohamed |
| Funding Agency and Grant Number |
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| Corresponding Author |
Elsayed Abdelkreem, Assistant Professor, MD, PhD, Department of Pediatrics, Faculty of Medicine, Sohag University, Sohag University Street, Nasser City 82524, Sohag, Egypt. d.elsayedmohammed@med.sohag.edu.eg |
| Key Words |
Bronchiolitis; Cholecalciferol; Length of hospital stay; Respiratory tract infections; Vitamin D deficiency |
| Core Tip |
Vitamin D deficiency has been linked to bronchiolitis, yet the therapeutic benefit of supplementation remains uncertain. In this randomized controlled trial, a single intramuscular dose of 200000 IU vitamin D3 significantly shortened hospital stay and reduced oxygen and intravenous fluid requirements in children with bronchiolitis who were vitamin D deficient, but not in those with sufficient levels. These results suggest that targeted supplementation may improve outcomes in deficient children, supporting a test-and-treat strategy. |
| Citation |
Abdelkreem E, Labeeb YS, Mohamed MA. Efficacy of vitamin D supplementation for children with acute bronchiolitis: A randomized controlled trial. World J Clin Pediatr 2025; In press |
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Received |
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2025-09-22 09:58 |
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Peer-Review Started |
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2025-09-22 09:58 |
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First Decision by Editorial Office Director |
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2025-10-10 09:05 |
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Return for Revision |
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2025-10-10 09:05 |
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Revised |
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2025-10-20 18:56 |
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Publication Fee Transferred |
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2025-10-26 16:01 |
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Second Decision by Editor |
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2025-12-03 02:37 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2025-12-03 09:07 |
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Articles in Press |
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2025-12-03 09:07 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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| ISSN |
2219-2808 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
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