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Publication Name World Journal of Clinical Pediatrics
Manuscript ID 114465
Country Egypt
Category Pediatrics
Manuscript Type Randomized Controlled Trial
Article Title Efficacy of vitamin D supplementation for children with acute bronchiolitis: A randomized controlled trial
Manuscript Source Unsolicited Manuscript
All Author List Elsayed Abdelkreem, Yostena Safwat Labeeb and Mostafa Ashry Mohamed
Funding Agency and Grant Number
Corresponding Author Elsayed Abdelkreem, Assistant Professor, MD, PhD, Department of Pediatrics, Faculty of Medicine, Sohag University, Sohag University Street, Nasser City 82524, Sohag, Egypt. d.elsayedmohammed@med.sohag.edu.eg
Key Words Bronchiolitis; Cholecalciferol; Length of hospital stay; Respiratory tract infections; Vitamin D deficiency
Core Tip Vitamin D deficiency has been linked to bronchiolitis, yet the therapeutic benefit of supplementation remains uncertain. In this randomized controlled trial, a single intramuscular dose of 200000 IU vitamin D3 significantly shortened hospital stay and reduced oxygen and intravenous fluid requirements in children with bronchiolitis who were vitamin D deficient, but not in those with sufficient levels. These results suggest that targeted supplementation may improve outcomes in deficient children, supporting a test-and-treat strategy.
Citation Abdelkreem E, Labeeb YS, Mohamed MA. Efficacy of vitamin D supplementation for children with acute bronchiolitis: A randomized controlled trial. World J Clin Pediatr 2025; In press
Received
2025-09-22 09:58
Peer-Review Started
2025-09-22 09:58
First Decision by Editorial Office Director
2025-10-10 09:05
Return for Revision
2025-10-10 09:05
Revised
2025-10-20 18:56
Publication Fee Transferred
2025-10-26 16:01
Second Decision by Editor
2025-12-03 02:37
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2025-12-03 09:07
Articles in Press
2025-12-03 09:07
Edit the Manuscript by Language Editor
Typeset the Manuscript
ISSN 2219-2808 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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